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Results: 4
Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development
Ronja S. Adam, Sanne M. van Neerven, Cayetano Pleguezuelos-Manzano, Salvatore Simmini, Nicolas Léveillé, Nina E. de Groot, Andrew N. Holding, Florian Markowetz, Louis Vermeulen
Dec 03, 2020
Abstract: Background: Cancer results from the accumulation of mutations leading to the acquisition of cancer promoting characteristics such as increased proliferation and resistance to cell death. In colorectal cancer, an early...
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K.
John RP Knight, Nikola Vlahov, David M Gay, Rachel A Ridgway, William James Faller, Christopher Proud, Giovanna R Mallucci, Tobias von der Haar, Christopher Mark Smales, Anne E Willis, Owen J Sansom
Jan 28, 2022
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K.
John RP Knight, Nikola Vlahov, David M Gay, Rachel A Ridgway, William James Faller, Christopher Proud, Giovanna Mallucci, Tobias von der Haar, Christopher Mark Smales, Anne Willis, Owen J Sansom
Jan 04, 2022
Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development.
Ronja S Adam, Sanne M van Neerven, Cayetano Pleguezuelos-Manzano, Salvatore Simmini, Nicolas Léveillé, Nina E de Groot, Andrew N Holding, Florian Markowetz, Louis Vermeulen
Feb 05, 2021
BACKGROUND: Cancer results from the accumulation of mutations leading to the acquisition of cancer promoting characteristics such as increased proliferation and resistance to cell death. In colorectal cancer, an early mutation...