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Congenital heart disease (CHD) is the most common class of human birth defects, with a prevalence of 0.9% of births. However, two-thirds of cases have an unknown cause, and many of these are thought to be caused by in utero...

Animals Aorta Thoracic Biomarkers cardiovascular system Cell Differentiation Coronary Vessels Dietary Supplements Edema Embryo Mammalian Embryonic Development Female Gene Expression Profiling Gene-Environment Interaction Green Fluorescent Proteins Iron Iron Deficiencies Lymphatic Vessels Mice Inbred C57BL Myocardium Myocytes Cardiac Penetrance Phenotype Pregnancy Signal Transduction Stem Cells Transgenes Tretinoin

Animals Apoptosis Cell Line Cell Survival Chemokine CXCL12 Chickens Clathrin Heavy Chains Culture Media Gene Expression Profiling Gene Expression Regulation Iron Deficiencies Oligonucleotide Array Sequence Analysis Precursor Cells B-Lymphoid Promoter Regions Genetic Receptors CXCR4 Signal Transduction Tetracycline Transferrin

One-third of children falter in cognitive development by pre-school age. Iron plays an important role in many neurodevelopmental processes, and animal studies suggest that iron sufficiency in pregnancy and infancy is...

brain development cognitive Infancy Iron deficiency Motor pre-school Pregnancy socio-emotional Adult Anemia Iron-Deficiency Brain Child Preschool Dietary Supplements Female Humans Infant Infant Nutritional Physiological Phenomena Infant Newborn Iron Iron Deficiencies Iron Dietary Male Maternal Nutritional Physiological Phenomena Neurodevelopmental Disorders Nutritional Status Pregnancy Prenatal Care

Hepcidin regulates systemic iron homeostasis. Suppression of hepcidin expression occurs physiologically in iron deficiency and increased erythropoiesis but is pathologic in thalassemia and hemochromatosis. Here we show that...

Acetylation Amino Acid Motifs Animals Epigenesis Genetic Erythropoietin Gene Expression Regulation Hepcidins Histone Deacetylases Histones Humans Iron Deficiencies Male Mice Inbred C57BL Promoter Regions Genetic

Iron acquisition is critical for life. Ferroportin (FPN) exports iron from mature erythrocytes, and deletion of the Fpn gene results in hemolytic anemia and increased fatality in malaria-infected mice. The FPN Q248H mutation...

Amino Acid Substitution Anemia Bacteremia Cation Transport Proteins Erythrocytes Female Humans Infant Infant Newborn Iron Iron Deficiencies Malaria Male Mutation Missense

Iron deficiency remains the largest nutritional deficiency worldwide and the main cause of anaemia. Severe iron deficiency leads to anaemia known as iron deficiency anaemia (IDA), which affects a total of 1·24 billion people...

IDA iron deficiency anaemia LMIC low- and middle-income countries Capacity building Iron deficiency Iron deficiency anaemia iron supplementation Adult Anemia Iron-Deficiency Child Communicable Diseases Cost of Illness Developing Countries Dietary Supplements Female Humans Iron Deficiencies Male Pregnancy

Anaemia control programmes in India are hampered by a lack of representative evidence on anaemia prevalence, burden and associated factors for adolescents. The aim of this study was to: (1) describe the national and subnational...

india Adolescent anaemia Micronutrients Public Health Adolescent Anemia Anemia Iron-Deficiency Child Female Ferritins Hemoglobinopathies Humans india Iron Deficiencies Male Malnutrition Micronutrients prevalence Vitamin A Zinc

AIMS: Novel oral iron supplements may be associated with a reduced incidence of adverse drug reactions compared to standard treatments of iron deficiency anaemia. The aim was to establish their value-based price under conditions...

cost and cost analysis cost-effectiveness Iron iron-deficiency anaemia Anemia Iron-Deficiency Cost-Benefit Analysis Drug-Related Side Effects and Adverse Reactions Female Humans Iron Iron Deficiencies Salts