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Hi-C KOREF Korean reference genome PromethION nanopore sequencing single-molecule sequencing Chromosomes Human Contig Mapping Cost-Benefit Analysis Databases Genetic High-Throughput Nucleotide Sequencing Humans Republic of Korea single molecule imaging whole genome sequencing

BACKGROUND:Long DNA reads produced by single-molecule and pore-based sequencers are more suitable for assembly and structural variation discovery than short-read DNA fragments. For de novo assembly, Pacific Biosciences (PacBio)...

Hi-C single-molecule sequencing nanopore sequencing KOREF Korean reference genome PromethION