Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer
Rachael E. Clifford,
Naren Govindarajah,
David Bowden,
Paul Sutton,
Mark Glenn,
Mahnaz Darvish-Damavandi,
Simon Buczacki,
Ultan McDermott,
Zdzislaw Szulc,
Besim Ogretmen,
Jason L. Parsons,
Dale Vimalachandran
Dec 22, 2020
Previous work utilizing proteomic and immunohistochemical analyses has identified that high levels of acid ceramidase (AC) expression confers a poorer response to neoadjuvant treatment in locally advanced rectal cancer. We aimed...