Search

Results: 7

A subset of dendritic cells induces CD4+ T cells to produce IFN-? by an IL-12-independent but CD70-dependent mechanism in vivo

Helena Soares, Haena Waechter, Nicolas Glaichenhaus

Jan 01, 0001

Interferon (IFN)-?, a cytokine critical for resistance to infection and tumors, is produced by CD4+ helper T lymphocytes after stimulation by cultured dendritic cells (DCs) that secrete a cofactor, interleukin (IL)-12. We have...

antigen presenting cell CD4+ T lymphocyte Cell Differentiation dendritic cell Leishmania major protozoal proteins

Published by: Rockefeller University

View Article

Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran.

Bibi Razieh Hosseini Farash, Seyed Ali Akbar Shamsian, Masoud Mohajery, Abdolmajid Fata, Fatemeh Sadabadi, Fariba Berenji, Pietro Mastroeni, Elham Poustchi, Elham Moghaddas, Ghodratollah Salehi Sangani, Gholamreza Farnoosh

Feb 11, 2021

The province of Khorasan-Razavi in the North East of Iran is an endemic area for anthroponotic cutaneous leishmaniasis (ACL caused mainly by Leishmania tropica) and zoonotic cutaneous leishmaniasis (ZCL caused mainly by...

Cutaneous leishmaniasis Leishmania major Leishmania tropica molecular and immunological techniques Khorasan-Razavi province Adult Animals Electrophoresis Enzyme-Linked Immunosorbent Assay Humans Incidence Iran Leishmania major Leishmania tropica Leishmaniasis Cutaneous Polymerase Chain Reaction prevalence Random Amplified Polymorphic DNA Technique Zoonoses

Published by:

Cover Image for Sequencing abasic sites in DNA at single-nucleotide resolution.

View Article

Whole genome experimental maps of DNA G-quadruplexes in multiple species.

Giovanni Marsico, Vicki S Chambers, Aleksandr B Sahakyan, Patrick McCauley, Jonathan M Boutell, Marco Di Antonio, Shankar Balasubramanian

Mar 08, 2019

Aminoquinolines Animals Arabidopsis Base Sequence Caenorhabditis elegans Chromosome Mapping Drosophila melanogaster Escherichia coli G-Quadruplexes Genome High-Throughput Nucleotide Sequencing Humans Leishmania major Mice Phylogeny Picolinic Acids Plasmodium falciparum Rhodobacter sphaeroides Saccharomyces cerevisiae Trypanosoma brucei brucei Zebrafish

Published by:

View Article

Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major.

Susanne Kramer, Nicola C Kimblin, Mark Carrington

Jun 16, 2011

Genome-Wide Association Study Leishmania major Protein Structure Tertiary RNA-Binding Proteins Trypanosoma brucei brucei Trypanosoma cruzi Ubiquitination Zinc Fingers

Published by:

Cover Image for Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania.

View Article

Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity

Ines Matos, Olga Mizenina, Ashira Lubkin, Ralph M. Steinman, Juliana Idoyaga

Jan 01, 0001

Efficient vaccination against the parasite Leishmania major, the causative agent of human cutaneous leishmaniasis, requires development of type 1 T-helper (Th1) CD4+ T cell immunity. Because of their unique capacity to initiate...

CD4+ T lymphocyte dendritic cell Genetic Engineering Immunization protozoal protein tumor necrosis factor Leishmania major

Published by: Rockefeller University