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Evi1 Counteracts Anti-Leukemic and Stem Cell Inhibitory Effects of All-Trans Retinoic Acid on Flt3-ITD/Npm1c-Driven Acute Myeloid Leukemia Cells.
Chi Huu Nguyen, Alexander M Grandits, George S Vassiliou, Philipp B Staber, Gerwin Heller, Rotraud Wieser
Oct 19, 2020
All-trans retinoic acid (atRA) has a dramatic impact on the survival of patients with acute promyelocytic leukemia, but its therapeutic value in other types of acute myeloid leukemia (AML) has so far remained unclear. Given that...