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No relationship between early postnatal testosterone concentrations and autistic traits in 18 to 30-month-old children.
Karson TF Kung, Mihaela Constantinescu, Wendy V Browne, Rebecca M Noorderhaven, Melissa Hines
Feb 15, 2016
autism gender differences Postnatal development Sex differences Testosterone Adult Autism spectrum disorder Birth Weight Child Development Child Preschool Female Humans Infant Male Maternal Age Parents Paternal Age Risk Factors Saliva Siblings Surveys and Questionnaires Symptom Assessment Testosterone
Psychological well-being of identity-release egg donation parents with infants.
STUDY QUESTION: What are the psychological health, relationship quality and perceived social support outcomes of heterosexual couples who have conceived an infant through identity-release egg donation? SUMMARY ANSWER: Parents'...
Assisted Reproductive Technologies Egg donation gamete donation identity-release parental psychological health relationship quality social support Age Factors Anxiety Fathers Female Fertilization Fertilization in Vitro Humans Infant Infant Newborn Insemination Artificial Heterologous Male Maternal Age Mothers Oocyte Donation Parenting Parents Paternal Age social support Surveys and Questionnaires United Kingdom
Age at menarche and the risk of operative delivery.
Hsu Phern Chong, J Frederik Frøen, Sylvia Richardson, Benoit Liquet, D Stephen Charnock-Jones, Gordon CS Smith
Apr 18, 2018
OBJECTIVES: We sought to evaluate the impact of later menarche on the risk of operative delivery. POPULATION: We studied 38,069 eligible women (first labors at term with a singleton infant in a cephalic presentation) from the...
Menarche cesarean Maternal Age operative vaginal delivery Adult Age Factors Cesarean Section delivery Obstetric EXTRACTION Obstetrical Female Humans Infant Newborn Male Menarche Norway Obstetric Labor Complications Obstetrical Forceps Pregnancy Risk Factors Term Birth Vacuum Extraction Obstetrical Young Adult
An Unbiased Lipidomics Approach Identifies Early Second Trimester Lipids Predictive of Maternal Glycemic Traits and Gestational Diabetes Mellitus.
Liangjian Lu, Albert Koulman, Clive J Petry, Benjamin Jenkins, Lee Matthews, Ieuan A Hughes, Carlo L Acerini, Ken K Ong, David B Dunger
Nov 03, 2016
Perinatal mortality associated with induction of labour versus expectant management in nulliparous women aged 35 years or over
Hannah E Knight, David A Cromwell, Ipek Gurol-Urganci, Katie Harron, Jan H van der Meulen, Gordon CS Smith
Mar 09, 2018
BACKGROUND: A recent randomised controlled trial (RCT) demonstrated that induction of labour at 39 weeks of gestational age has no short-term adverse effect on the mother or infant among nulliparous women aged ≥35 years....
Randomized Trial of Labor Induction in Women 35 Years of Age or Older.
Kate F Walker, George J Bugg, Marion Macpherson, Carol McCormick, Nicky Grace, Chris Wildsmith, Lucy Bradshaw, Gordon CS Smith, James G Thornton, 35/39 Trial Group
Dec 09, 2015
Barriers to completing oral glucose tolerance testing in women at risk of gestational diabetes.
Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single-cell analysis.
Juan Castillo-Fernandez, Erika Herrera-Puerta, Hannah Demond, Stephen J Clark, Courtney W Hanna, Myriam Hemberger, Gavin Kelsey
Jan 11, 2021
Advancing maternal age causes a progressive reduction in fertility. The decline in developmental competence of the oocyte with age is likely to be a consequence of multiple contributory factors. Loss of epigenetic quality of the...
Association of preeclampsia with anthropometric measures and blood pressure in Indian children.
Karuna Randhir, Hemlata Pisal, Vrushali Kadam, Amrita Khaire-Ghadge, Nandini Malshe, Ruma Deshpande, Sonali Palkar, Sanjay Lalwani, Kalyanaraman Kumaran, Chittaranjan Yajnik, Clive Osmond, Caroline Fall, Sadhana Joshi
May 05, 2020
BACKGROUND AND OBJECTIVE: Birth weight and post-natal growth are important predictors of adult health. Preeclampsia (PE) is associated with low birth weight and may have long term effects on the health of the children. The...
Intergenerational transmission of parenting
Vaishnavee Madden, Jill Domoney, Katie Aumayer, Vaheshta Sethna, Jane Iles, Isabelle Hubbard, Andreas Giannakakis, Lamprini Psychogiou, Paul Ramchandani
Jan 08, 2019
BACKGROUND: The quality of parenting is associated with a wide range of child and adult outcomes, and there is evidence to suggest that some aspects of parenting show patterns of intergenerational transmission. This study aimed...
The effect of delaying childbirth on primary cesarean section rates.
Gordon CS Smith, Yolande Cordeaux, Ian R White, Dharmintra Pasupathy, Hannah Missfelder-Lobos, Jill P Pell, D Stephen Charnock-Jones, Michael Fleming
Aug 10, 2020
BACKGROUND: The relationship between population trends in delaying childbirth and rising rates of primary cesarean delivery is unclear. The aims of the present study were (1) to characterize the association between maternal age...
Foetal oestrogens and autism.
Simon Baron-Cohen, Alexandros Tsompanidis, Bonnie Auyeung, Bent Nørgaard-Pedersen, David M Hougaard, Morsi Abdallah, Arieh Cohen, Alexa Pohl
Jun 22, 2020
Elevated latent prenatal steroidogenic activity has been found in the amniotic fluid of autistic boys, based on measuring prenatal androgens and other steroid hormones. To date, it is unclear if other prenatal steroids also...
Factors influencing the likelihood of instrumental delivery success.
Genome-wide analysis identifies 12 loci influencing human reproductive behavior.
N Barban, R Jansen, R de Vlaming, A Vaez, JJ Mandemakers, FC Tropf, X Shen, JF Wilson, DI Chasman, IM Nolte, V Tragante, SW van der Laan, JRB Perry, A Kong, BIOS Consortium, TS Ahluwalia, E Albrecht, L Yerges-Armstrong, G Atzmon, K Auro, K Ayers, A Bakshi, D Ben-Avraham, K Berger, A Bergman, L Bertram, LF Bielak, G Bjornsdottir, MJ Bonder, L Broer, M Bui, C Barbieri, A Cavadino, JE Chavarro, C Turman, MP Concas, HJ Cordell, G Davies, P Eibich, N Eriksson, T Esko, J Eriksson, F Falahi, JF Felix, MA Fontana, L Franke, I Gandin, AJ Gaskins, C Gieger, EP Gunderson, X Guo, C Hayward, C He, E Hofer, H Huang, PK Joshi, S Kanoni, R Karlsson, S Kiechl, A Kifley, A Kluttig, P Kraft, V Lagou, C Lecoeur, J Lahti, R Li-Gao, PA Lind, T Liu, E Makalic, C Mamasoula, L Matteson, H Mbarek, PF McArdle, G McMahon, SFW Meddens, E Mihailov, M Miller, SA Missmer, C Monnereau, PJ van der Most, R Myhre, MA Nalls, T Nutile, IP Kalafati, E Porcu, I Prokopenko, KB Rajan, J Rich-Edwards, CA Rietveld, A Robino, LM Rose, R Rueedi, KA Ryan, Y Saba, D Schmidt, JA Smith, L Stolk, E Streeten, A Tönjes, G Thorleifsson, S Ulivi, J Wedenoja, J Wellmann, P Willeit, J Yao, L Yengo, JH Zhao, W Zhao, DV Zhernakova, N Amin, H Andrews, B Balkau, N Barzilai, S Bergmann, G Biino, H Bisgaard, K Bønnelykke, DI Boomsma, JE Buring, H Campbell, S Cappellani, M Ciullo, SR Cox, F Cucca, D Toniolo, G Davey-Smith, IJ Deary, G Dedoussis, P Deloukas, CM van Duijn, EJC de Geus, JG Eriksson, DA Evans, JD Faul, CF Sala, P Froguel, P Gasparini, G Girotto, H-J Grabe, KH Greiser, PJF Groenen, HG de Haan, J Haerting, TB Harris, AC Heath, K Heikkilä, A Hofman, G Homuth, EG Holliday, J Hopper, E Hyppönen, B Jacobsson, VWV Jaddoe, M Johannesson, A Jugessur, M Kähönen, E Kajantie, SLR Kardia, B Keavney, I Kolcic, P Koponen, P Kovacs, F Kronenberg, Z Kutalik, M La Bianca, G Lachance, WG Iacono, S Lai, T Lehtimäki, DC Liewald, Lifelines Cohort Study, CM Lindgren, Y Liu, R Luben, M Lucht, R Luoto, P Magnus, PKE Magnusson, NG Martin, M McGue, R McQuillan, SE Medland, C Meisinger, D Mellström, A Metspalu, M Traglia, L Milani, P Mitchell, GW Montgomery, D Mook-Kanamori, R de Mutsert, EA Nohr, C Ohlsson, J Olsen, KK Ong, L Paternoster, A Pattie, BWJH Penninx, M Perola, PA Peyser, M Pirastu, O Polasek, C Power, J Kaprio, LJ Raffel, K Räikkönen, O Raitakari, PM Ridker, SM Ring, K Roll, I Rudan, D Ruggiero, D Rujescu, V Salomaa, D Schlessinger, H Schmidt, R Schmidt, N Schupf, J Smit, R Sorice, TD Spector, JM Starr, D Stöckl, K Strauch, M Stumvoll, MA Swertz, U Thorsteinsdottir, AR Thurik, NJ Timpson, JY Tung, AG Uitterlinden, S Vaccargiu, J Viikari, V Vitart, H Völzke, P Vollenweider, D Vuckovic, J Waage, GG Wagner, JJ Wang, NJ Wareham, DR Weir, G Willemsen, J Willeit, AF Wright, KT Zondervan, K Stefansson, RF Krueger, JJ Lee, DJ Benjamin, D Cesarini, PD Koellinger, M den Hoed, H Snieder, MC Mills
Nov 30, 2016
The genetic architecture of human reproductive behavior-age at first birth (AFB) and number of children ever born (NEB)-has a strong relationship with fitness, human development, infertility and risk of neuropsychiatric...
Population and fertility by age and sex for 195 countries and territories, 1950-2017
GBD 2017 Population and Fertility Collaborators
Sep 18, 2019
BACKGROUND: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates of...
Screening and prevention of stillbirth.
Gordon CS Smith
Nov 02, 2016
Biomarkers intervention screening Stillbirth ULTRASOUND ABO Blood-Group System Abortion Spontaneous Black People Cesarean Section delivery Obstetric Diabetes mellitus Female Humans Infant Newborn Labor Induced Maternal Age obesity Parity Perinatal Death Pregnancy Pregnancy Complications Pregnancy Multiple Pregnancy-Associated Plasma Protein-A Prenatal Diagnosis Risk Assessment Risk Factors Stillbirth Substance-Related Disorders Tobacco Smoke Pollution Ultrasonography Prenatal alpha-Fetoproteins
Maternal age, autistic-like traits and mentalizing as predictors of child autistic-like traits in a population-based cohort.
Novika Purnama Sari, Pauline W Jansen, Laura ME Blanken, Amber NV Ruigrok, Peter Prinzie, Henning Tiemeier, Simon Baron-Cohen, Marinus H van IJzendoorn, Tonya White
Jul 16, 2022
BACKGROUND: Many empirical studies suggest that higher maternal age increases the likelihood of having an autistic child. However, little is known about factors that may explain this relationship or if higher maternal age is...
Maternal age, autistic-like traits and mentalizing as predictors of child autistic-like traits in a population-based cohort.
Induction of labour versus expectant management for nulliparous women over 35 years of age
Kate F Walker, George Bugg, Marion Macpherson, Carol McCormick, Chris Wildsmith, Gordon Smith, Jim Thornton
Aug 08, 2017
Decidualisation and placentation defects are a major cause of age-related reproductive decline.
Laura Woods, Vicente Perez-Garcia, Jens Kieckbusch, Xiaoqiu Wang, Francesco DeMayo, Francesco Colucci, Myriam Hemberger
Dec 17, 2018
Advanced maternal age compromises fetal growth and induces sex-specific changes in placental phenotype in rats.
Advanced maternal age is associated with an increased risk of pregnancy complications. It programmes sex-specific cardiovascular dysfunction in rat offspring, however the intrauterine mechanisms involved remain unknown. This...
Reduced size at birth and persisting reductions in adiposity in recent, compared with earlier, cohorts of infants born to mothers with gestational diabetes mellitus.
Philippa M Prentice, Laurentya Olga, Clive J Petry, David Simmons, Helen R Murphy, Ieuan A Hughes, Carlo L Acerini, Ken K Ong, David B Dunger
Jul 04, 2019
Adiposity Gestational diabetes mellitus growth Infancy Macrosomia Maternal hyperglycaemia Offspring Skinfold Thickness Weight Gain Adiposity Adult Anthropometry Birth Weight Body Size Child Preschool Diabetes Gestational Female Fetal Macrosomia Glucose Tolerance Test Humans Infant Infant Newborn Life Style Male Maternal Age obesity Phenotype Pregnancy Prospective Studies Retrospective Studies