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Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence.
Sara Kohnke, Sophie Buller, Danae Nuzzaci, Katherine Ridley, Brian Lam, Helena Pivonkova, Marie A Bentsen, Kimberly M Alonge, Chao Zhao, John Tadross, Staffan Holmqvist, Takahiro Shimizu, Hannah Hathaway, Huiliang Li, Wendy Macklin, Michael W Schwartz, William D Richardson, Giles SH Yeo, Robin Jm Franklin, Ragnhildur T Karadottir, David H Rowitch, Clemence Blouet
May 11, 2021
The mediobasal hypothalamus (MBH; arcuate nucleus of the hypothalamus [ARH] and median eminence [ME]) is a key nutrient sensing site for the production of the complex homeostatic feedback responses required for the maintenance...
Energy balance Glucose homeostasis Hypothalamus Median eminence Nutrition obesity oligodendrocyte Perineuronal nets plasticity Adult Animals Cell Differentiation Cell Lineage Cell Proliferation Humans Male Mechanistic Target of Rapamycin Complex 1 Median eminence Mice Inbred C57BL Nerve Net Nutritional Physiological Phenomena Oligodendroglia Single-Cell Analysis Transcriptome