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Monocytes Latently Infected with Human Cytomegalovirus Evade Neutrophil Killing.
Elizabeth Elder, Benjamin Krishna, James Williamson, Yusuf Aslam, Neda Farahi, Alexander Wood, Veronika Romashova, Kate Roche, Eain Murphy, Edwin Chilvers, Paul J Lehner, John Sinclair, Emma Poole
Feb 01, 2019
One site of latency of human cytomegalovirus (HCMV) in vivo is in undifferentiated cells of the myeloid lineage. Although latently infected cells are known to evade host T cell responses by suppression of T cell effector...
TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis.
Siân P Cartland, Scott W Genner, Gonzalo J Martínez, Stacy Robertson, Maaike Kockx, Ruby Cy Lin, John F O'Sullivan, Yen Chin Koay, Pradeep Manuneedhi Cholan, Melkam A Kebede, Andrew J Murphy, Seth Masters, Martin R Bennett, Wendy Jessup, Leonard Kritharides, Carolyn Geczy, Sanjay Patel, Mary M Kavurma
Mar 19, 2019
Circulating tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) levels are reduced in patients with cardiovascular disease, and TRAIL gene deletion in mice exacerbates atherosclerosis and inflammation. How...