Incident disease associations with mosaic chromosomal alterations on autosomes, X and Y chromosomes
Shu-Hong Lin,
Derek W Brown,
Brandon Rose,
Felix Day,
Olivia W Lee,
Sairah M Khan,
Jada Hislop,
Stephen J Chanock,
John RB Perry,
Mitchell J Machiela
Aug 02, 2021
BACKGROUND: Mosaic chromosomal alterations (mCAs) are large chromosomal gains, losses and copy-neutral losses of heterozygosity (LOH) in peripheral leukocytes. While many individuals with detectable mCAs have no notable adverse...