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The financial outcome of traumatic brain injury
Effects of Prone Position and Positive End-Expiratory Pressure on Noninvasive Estimators of ICP
Chiara Robba, Nicola Luigi Bragazzi, Alessandro Bertuccio, Danilo Cardim, Joseph Donnelly, Mypinder Sekhon, Andrea Lavinio, Derek Duane, Rowan Burnstein, Basil Matta, Susanna Bacigaluppi, Marco Lattuada, Marek Czosnyka
Mar 18, 2016
Techniques for chronic monitoring of brain activity in freely moving sheep using wireless EEG recording.
Behaviour Epilepsy Huntington’s disease Large animal Neurodegenerative disease Ovine Pig Sleep Anesthesia Animals Brain Electrocorticography Electrodes Implanted Longitudinal Studies Membrane Proteins Models Animal Monitoring Physiologic Motor Activity Mutation Neurosurgical Procedures Sheep Domestic Signal Processing Computer-Assisted Wireless Technology
The cortical organization of language
Connectomics is the production and study of detailed "connection" maps within the nervous system. With unprecedented advances in imaging and high-performance computing, the construction of individualized connectomes for routine...
The Neurology and Neurosurgery Interest Group (NANSIG)-ten years of cultivating interest in clinical neurosciences.
Jay J Park, Setthasorn Zhi Yang Ooi, Conor S Gillespie, Soham Bandyopadhyay, Yasir A Chowdhury, Georgios Solomou, Melissa Gough, Ulrick Sidney Kanmounye, Alvaro Yanez Touzet, Michael TC Poon, Andreas K Demetriades, Michael D Jenkinson, Alistair Jenkins, Neurology and Neurosurgery Interest Group (NANSIG)
Mar 31, 2022
Collaboration and successful teamworking are important components of clinical practise, and these skills should be cultivated early in medical school. The breadth of current medical school curricula means that students often...
Spatio-spectral classification of hyperspectral images for brain cancer detection during surgical operations.
Himar Fabelo, Samuel Ortega, Daniele Ravi, B Ravi Kiran, Coralia Sosa, Diederik Bulters, Gustavo M Callicó, Harry Bulstrode, Adam Szolna, Juan F Piñeiro, Silvester Kabwama, Daniel Madroñal, Raquel Lazcano, Aruma J-O'Shanahan, Sara Bisshopp, María Hernández, Abelardo Báez, Guang-Zhong Yang, Bogdan Stanciulescu, Rubén Salvador, Eduardo Juárez, Roberto Sarmiento
Apr 12, 2019
Surgery for brain cancer is a major problem in neurosurgery. The diffuse infiltration into the surrounding normal brain by these tumors makes their accurate identification by the naked eye difficult. Since surgery is the common...
Integrated care pathways in neurosurgery
Keng Siang Lee, Stefan Yordanov, Daniel Stubbs, Ellie Edlmann, Alexis Joannides, Benjamin Davies
Jul 29, 2021
INTRODUCTION: Integrated care pathways (ICPs) are a pre-defined framework of evidence based, multidisciplinary practice for specific patients. They have the potential to enhance continuity of care, patient safety, patient...
Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities
Edoardo Picetti, Fausto Catena, Fikri Abu-Zidan, Luca Ansaloni, Rocco A Armonda, Miklosh Bala, Zsolt J Balogh, Alessandro Bertuccio, Walt L Biffl, Pierre Bouzat, Andras Buki, Davide Cerasti, Randall M Chesnut, Giuseppe Citerio, Federico Coccolini, Raul Coimbra, Carlo Coniglio, Enrico Fainardi, Deepak Gupta, Jennifer M Gurney, Gregory WJ Hawryluk, Raimund Helbok, Peter JA Hutchinson, Corrado Iaccarino, Angelos Kolias, Ronald W Maier, Matthew J Martin, Geert Meyfroidt, David O Okonkwo, Frank Rasulo, Sandro Rizoli, Andres Rubiano, Juan Sahuquillo, Valerie G Sams, Franco Servadei, Deepak Sharma, Lori Shutter, Philip F Stahel, Fabio S Taccone, Andrew Udy, Tommaso Zoerle, Vanni Agnoletti, Francesca Bravi, Belinda De Simone, Yoram Kluger, Costanza Martino, Ernest E Moore, Massimo Sartelli, Dieter Weber, Chiara Robba
Apr 07, 2023
Functional connectivity networks for preoperative brain mapping in neurosurgery.
BOLD = blood oxygenation level–dependent DMN = default mode network InstaCorr ME-ICA ME-ICA = multiecho independent component analysis MNI = Montreal Neurological Institut SCA = seed-based connectivity analysis SMN = sensorimotor network Default mode network diagnostic and operative techniques fMRI = functional MRI functional connectivity Glioblastoma multiecho independent component analysis oncology resting-state functional MRI rsfMRI = resting-state fMRI seed-based connectivity Adult Aged Brain Brain Mapping Brain Neoplasms Glioblastoma Humans Magnetic Resonance Imaging Middle Aged Nerve Net Neural Pathways Neurosurgical Procedures Temporal Lobe
Multidisciplinary management of acromegaly
Andrea Giustina, Garni Barkhoudarian, Albert Beckers, Anat Ben-Shlomo, Nienke Biermasz, Beverly Biller, Cesar Boguszewski, Marek Bolanowski, Jens Bollerslev, Vivien Bonert, Marcello D Bronstein, Michael Buchfelder, Felipe Casanueva, Philippe Chanson, David Clemmons, Maria Fleseriu, Anna Maria Formenti, Pamela Freda, Monica Gadelha, Eliza Geer, Mark Gurnell, Anthony P Heaney, Ken KY Ho, Adriana G Ioachimescu, Steven Lamberts, Edward Laws, Marco Losa, Pietro Maffei, Adam Mamelak, Moises Mercado, Mark Molitch, Pietro Mortini, Alberto M Pereira, Stephan Petersenn, Kalmon Post, Manuel Puig-Domingo, Roberto Salvatori, Susan L Samson, Ilan Shimon, Christian Strasburger, Brooke Swearingen, Peter Trainer, Mary L Vance, John Wass, Margaret E Wierman, Kevin CJ Yuen, Maria Chiara Zatelli, Shlomo Melmed
Sep 02, 2020
The 13th Acromegaly Consensus Conference was held in November 2019 in Fort Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and neurosurgeons who considered optimal approaches for...
Neurosurgical procedures performed during residency in Europe-preliminary numbers and time trends.
Martin N Stienen, Jiri Bartek, Marcus A Czabanka, Christian F Freyschlag, Angelos Kolias, Sandro M Krieg, Wouter Moojen, Mirjam Renovanz, Nicolas Sampron, Sasan D Adib, Gerrit A Schubert, Andreas K Demetriades, Florian Ringel, Luca Regli, Karl Schaller, Torstein R Meling, EANS Young Neurosurgeons and EANS Training Committee
Mar 08, 2019
BACKGROUND: Differences in the postgraduate training programs of neurosurgical residents are suspected throughout Europe. The influence of working hour restrictions by the European Working Time Directive (WTD) 2003/88/EC on the...
The British Neurosurgical Trainee Research Collaborative
Aswin Chari, Aimun A Jamjoom, Ellie Edlmann, Aminul I Ahmed, Ian C Coulter, Ruichong Ma, Paul May, Paul M Brennan, Peter JA Hutchinson, Angelos G Kolias, British Neurosurgical Trainee Research Collaborative
Nov 28, 2018
Since its inception in 2012, the British Neurosurgical Trainee Research Collaborative (BNTRC) has established itself as a robust example of a trainee-led research collaborative. This article summarises the work of the...
State-of-the-art imaging for glioma surgery.
Diffuse gliomas are infiltrative primary brain tumors with a poor prognosis despite multimodal treatment. Maximum safe resection is recommended whenever feasible. The extent of resection (EOR) is positively correlated with...
Local alkylating chemotherapy applied immediately after 5-ALA guided resection of glioblastoma does not provide additional benefit.
William Sage, Mathew Guilfoyle, Catriona Luney, Adam Young, Rohitashwa Sinha, Donatella Sgubin, Joseph H McAbee, Ruichong Ma, Sarah Jefferies, Rajesh Jena, Fiona Harris, Kieren Allinson, Tomasz Matys, Wendi Qian, Thomas Santarius, Stephen Price, Colin Watts
May 25, 2018
Grade IV glioma is the most common and aggressive primary brain tumour. Gross total resection with 5-aminolevulinic acid (5-ALA) guided surgery combined with local chemotherapy (carmustine wafers) is an attractive treatment...
Prospective, multicentre study of external ventricular drainage-related infections in the UK and Ireland.
Aimun AB Jamjoom, Alexis J Joannides, Michael Tin-Chung Poon, Aswin Chari, Malik Zaben, Mutwakil AH Abdulla, Joy Roach, Laurence J Glancz, Anna Solth, John Duddy, Paul M Brennan, Roger Bayston, Diederik O Bulters, Conor L Mallucci, Michael D Jenkinson, William P Gray, Jothy Kandasamy, Peter J Hutchinson, Angelos G Kolias, Aminul I Ahmed, British Neurosurgical Trainee Research Collaborative
Jan 22, 2018
OBJECTIVES: External ventricular drain (EVD) insertion is a common neurosurgical procedure. EVD-related infection (ERI) is a major complication that can lead to morbidity and mortality. In this study, we aimed to establish a...
Adolescent Adult Aged Aged 80 and over Catheter-Related Infections Catheters Indwelling Cerebral Ventricles Child Child Preschool Female Humans Infant Infant Newborn Ireland Male Middle Aged Neurosurgical Procedures Postoperative Complications Proportional Hazards Models Prospective Studies Staphylococcal Infections United Kingdom Ventriculostomy Young Adult
Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities
Edoardo Picetti, Fausto Catena, Fikri Abu-Zidan, Luca Ansaloni, Rocco A Armonda, Miklosh Bala, Zsolt J Balogh, Alessandro Bertuccio, Walt L Biffl, Pierre Bouzat, Andras Buki, Davide Cerasti, Randall M Chesnut, Giuseppe Citerio, Federico Coccolini, Raul Coimbra, Carlo Coniglio, Enrico Fainardi, Deepak Gupta, Jennifer M Gurney, Gregory WJ Hawrylux, Raimund Helbok, Peter JA Hutchinson, Corrado Iaccarino, Angelos Kolias, Ronald W Maier, Matthew J Martin, Geert Meyfroidt, David O Okonkwo, Frank Rasulo, Sandro Rizoli, Andres Rubiano, Juan Sahuquillo, Valerie G Sams, Franco Servadei, Deepak Sharma, Lori Shutter, Philip F Stahel, Fabio S Taccone, Andrew Udy, Tommaso Zoerle, Vanni Agnoletti, Francesca Bravi, Belinda De Simone, Yoram Kluger, Costanza Martino, Ernest E Moore, Massimo Sartelli, Dieter Weber, Chiara Robba
Feb 10, 2023
BACKGROUND: Severe traumatic brain-injured (TBI) patients should be primarily admitted to a hub trauma center (hospital with neurosurgical capabilities) to allow immediate delivery of appropriate care in a specialized...
The IDEAL framework in neurosurgery
Helen CU Ota, Brandon G Smith, Alexander Alamri, Faith C Robertson, Hani Marcus, Allison Hirst, Marike Broekman, Peter Hutchinson, Peter McCulloch, Angelos Kolias
Jul 01, 2020
BACKGROUND: The Idea, Development, Exploration, Assessment and Long-term study (IDEAL) framework was created to provide a structured way for assessing and evaluating novel surgical techniques and devices. OBJECTIVES: The aim of...
Mapping whole brain connectivity changes
In neurosurgery there are several situations that require transgression of the temporal cortex. For example, a subset of patients with temporal lobe epilepsy require surgical resection (most typically, en-bloc anterior temporal...
Hinge/floating craniotomy as an alternative technique for cerebral decompression
Hugo Layard Horsfall, Midhun Mohan, B Indira Devi, Amos O Adeleye, Dhaval P Shukla, Dhananjaya Bhat, Mukhtar Khan, David J Clark, Aswin Chari, Franco Servadei, Tariq Khan, Andres M Rubiano, Peter J Hutchinson, Angelos G Kolias
Sep 17, 2019
When Time Is Critical, Is Informed Consent Less So? A Discussion of Patient Autonomy in Emergency Neurosurgery.
Ivo S Muskens, Saksham Gupta, Faith C Robertson, Wouter A Moojen, Angelos G Kolias, Wilco C Peul, Marike LD Broekman
Feb 06, 2019
Neurosurgical interventions frequently occur in an emergency setting. In this setting, patients often have impaired consciousness and are unable to directly express their values and wishes regarding their treatment. The limited...
CSF Rhinorrhea After Endonasal Intervention to the Skull Base (CRANIAL) - Part 2
CRANIAL Consortium
Oct 20, 2021
BACKGROUND: During the coronavirus disease 2019 (COVID-19) pandemic, concerns have been raised regarding the increased risk of perioperative mortality for patients with COVID-19, and the transmission risk to healthcare workers...
CRANIAL Consortium Skull Base Nasal Cavity Humans Cerebrospinal Fluid Rhinorrhea Postoperative Complications endoscopy Mass Screening Neurosurgical Procedures Cohort Studies Prospective Studies Adolescent Adult Aged Aged 80 and over Middle Aged Child Ireland Female Male Young Adult Preoperative Period Personal protective equipment United Kingdom covid-19 COVID-19 Testing
The evolution of an SBNS-accredited NANSIG simulated skills workshop for aspiring neurosurgical trainees
Melissa Gough, Georgios Solomou, Danyal Zaman Khan, Mohammed Kamel, Daniel Fountain, Ashwin Kumaria, Richard Ashpole, Saurabh Sinha, Nigel Mendoza
May 01, 2021
Stem Cell-Derived Dopamine Neurons
The use of stem cell-derived dopamine neurons or deep brain stimulation (DBS) represents two alternative approaches to treat Parkinson's Disease. DBS is a widely used FDA-approved treatment and stem cell-derived dopamine neuron...
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