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Melanin-Concentrating Hormone acts through hypothalamic kappa opioid system and p70S6K to stimulate acute food intake.
Amparo Romero-Picó, Estrella Sanchez-Rebordelo, Monica Imbernon, David González-Touceda, Cintia Folgueira, Ana Senra, Johan Fernø, Clémence Blouet, Roberto Cabrera, Margriet van Gestel, Roger A Adan, Miguel López, Rafael Maldonado, Ruben Nogueiras, Carlos Diéguez
Mar 12, 2018
Melanin-Concentrating Hormone (MCH) is one of the most relevant orexigenic factors specifically located in the lateral hypothalamic area (LHA), with its physiological relevance demonstrated in studies using several genetically...
Food intake Hypothalamus Kappa-opioid receptor melanin-concentrating hormone Melanin-Concentrating Hormone (MCH) (PubChem CID: 24868207) Naloxone hydrochloride (PubChem CID: 5464092) Norbinaltorphimine dyhydrochloride (norBNI) (PubChem CID: 5480230) Animals Appetite Depressants Dependovirus Eating Hypothalamic Area Lateral Hypothalamic Hormones MAP Kinase Signaling System Male Melanins Mice Mice Inbred C57BL Pituitary Hormones Rats Rats Sprague-Dawley Receptors Opioid kappa Ribosomal Protein S6 Kinases Ribosomal Protein S6 Kinases 70-kDa