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Results: 88
Tau pathology in early Alzheimer's disease is linked to selective disruptions in neurophysiological network dynamics.
Ece Kocagoncu, Andrew Quinn, Azadeh Firouzian, Elisa Cooper, Andrea Greve, Roger Gunn, Gary Green, Mark W Woolrich, Richard N Henson, Simon Lovestone, Deep and Frequent Phenotyping study team, James B Rowe
Mar 12, 2020
Understanding the role of Tau protein aggregation in the pathogenesis of Alzheimer's disease is critical for the development of new Tau-based therapeutic strategies to slow or prevent dementia. We tested the hypothesis that Tau...
Alzheimer's Disease Connectivity Graph theory MEG PET Tau Aged Aged 80 and over Alzheimer Disease Cognition Female Humans Magnetoencephalography Male Middle Aged Molecular Imaging Occipital Lobe Parietal Lobe Positron-Emission Tomography protein aggregation Pathological Synaptic Transmission tau Proteins
Neurological update
Timothy Rittman
Jul 07, 2021
Abstract: Neuroimaging for dementia has made remarkable progress in recent years, shedding light on diagnostic subtypes of dementia, predicting prognosis and monitoring pathology. This review covers some updates in the...
Motion estimation and correction for simultaneous PET/MR using SIRF and CIL
Richard Brown, Christoph Kolbitsch, Claire Delplancke, Evangelos Papoutsellis, Johannes Mayer, Evgueni Ovtchinnikov, Edoardo Pasca, Radhouene Neji, Casper da Costa-Luis, Ashley G Gillman, Matthias J Ehrhardt, Jamie R McClelland, Bjoern Eiben, Kris Thielemans
Aug 23, 2021
SIRF is a powerful PET/MR image reconstruction research tool for processing data and developing new algorithms. In this research, new developments to SIRF are presented, with focus on motion estimation and correction. SIRF's...
Modern imaging in Cushing's disease.
WA Bashari, D Gillett, J MacFarlane, AS Powlson, AG Kolias, R Mannion, DJ Scoffings, IA Mendichovszky, J Jones, HK Cheow, O Koulouri, M Gurnell
Oct 24, 2022
Imaging biomarkers in neurodegeneration
Peter N. E. Young, Mar Estarellas, Emma Coomans, Meera Srikrishna, Helen Beaumont, Anne Maass, Ashwin V. Venkataraman, Rikki Lissaman, Daniel Jiménez, Matthew J. Betts, Eimear McGlinchey, David Berron, Antoinette O’Connor, Nick C. Fox, Joana B. Pereira, William Jagust, Stephen F. Carter, Ross W. Paterson, Michael Schöll
Apr 27, 2021
Abstract: There is an increasing role for biological markers (biomarkers) in the understanding and diagnosis of neurodegenerative disorders. The application of imaging biomarkers specifically for the in vivo investigation of...
Multi-Modal Imaging in Down's Syndrome
In recent decades, the field of neuroimaging has experienced a surge of popularity and innovation which has led to significant advancements in the understanding of neurological disease, if not immediate clinical translation. In...
Computational and Literature Analysis of Photoinduced Electron Transfer in Fluorophores Containing Nitrogen Donors
Paige D'Elia
Jan 01, 0001
The rational design of chemical tools that only fluoresce when they react with a desired analyte is useful for biological imaging, detection, as well as for creation of other luminescent materials. These chemical tools are...
Published by: Ursinus College
Degradation of Cutin by Microbes Found In Compost
Rishabh Kancherla
Jan 01, 0001
Preliminary research into the degradation of cutin and PET by mesophilic and thermophilic microbes using GCMS and HPLC techniques.
PET plastic waste Cutin compost microbes Biochemistry Biochemistry, Biophysics, and Structural Biology Life Sciences Molecular Biology
Published by: Ursinus College
Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer’s disease
Abstract: Subjective cognitive decline (SCD) is regarded as the first clinical manifestation in the Alzheimer’s disease (AD) continuum. Investigating populations with SCD is important for understanding the early pathological...
Modern imaging of pituitary adenomas.
Waiel A Bashari, Russell Senanayake, Antía Fernández-Pombo, Daniel Gillett, Olympia Koulouri, Andrew S Powlson, Tomasz Matys, Daniel Scoffings, Heok Cheow, Iosif Mendichovszky, Mark Gurnell
Aug 21, 2019
Magnetic resonance imaging and positron emission tomography in anti-NMDA receptor encephalitis
Due to a variety of clinical manifestations anti-N-methyl-d-aspartate (NMDA) receptor encephalitis may be difficult to diagnose. Magnetic resonance imaging (MRI) may be used as a component of the workup for encephalopathy....
PET Imaging of Post-infarct Myocardial Inflammation
Abstract: Purpose of Review: To examine the use of positron emission tomography (PET) for imaging post-infarct myocardial inflammation and repair. Recent Findings: Dysregulated immune responses after myocardial infarction are...
Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer’s disease
Abstract: Subjective cognitive decline (SCD) is regarded as the first clinical manifestation in the Alzheimer’s disease (AD) continuum. Investigating populations with SCD is important for understanding the early pathological...
The pattern of amyloid accumulation in the brains of adults with Down syndrome.
Tiina Annus, Liam R Wilson, Young T Hong, Julio Acosta-Cabronero, Tim D Fryer, Arturo Cardenas-Blanco, Robert Smith, Istvan Boros, Jonathan P Coles, Franklin I Aigbirhio, David K Menon, Shahid H Zaman, Peter J Nestor, Anthony J Holland
Aug 18, 2015
Neuroinflammation in Neurodegenerative Diseases
Marco Aiello, Carlo Cavaliere, Dario Fiorenza, Andrea Duggento, Luca Passamonti, Nicola Toschi
Nov 07, 2018
Positron emission tomography (PET) provides spatially localized information about brain metabolism and function and innovative tracers have extended this potential to the study of neuroinflammation (NI), an important process in...
Beta amyloid deposition maps onto hippocampal and subiculum atrophy in dementia with Lewy bodies.
Elijah Mak, Paul C Donaghy, Elizabeth McKiernan, Michael J Firbank, Jim Lloyd, George S Petrides, Alan J Thomas, John T O'Brien
Nov 30, 2018
Severity of Psoriasis Associates With Aortic Vascular Inflammation Detected by FDG PET/CT and Neutrophil Activation in a Prospective Observational Study.
Haley B Naik, Balaji Natarajan, Elena Stansky, Mark A Ahlman, Heather Teague, Taufiq Salahuddin, Qimin Ng, Aditya A Joshi, Parasuram Krishnamoorthy, Jenny Dave, Shawn M Rose, Julia Doveikis, Martin P Playford, Ronald B Prussick, Alison Ehrlich, Mariana J Kaplan, Benjamin N Lockshin, Joel M Gelfand, Nehal N Mehta
Nov 04, 2015
CT PET Inflammation Neutrophils psoriasis vascular inflammation Adult Aortitis Biomarkers Case-Control Studies Female Fluorodeoxyglucose F18 Humans Immunity Innate Inflammation Mediators Leukocyte Count Male Middle Aged Multimodal Imaging Neutrophil Activation Neutrophils Positron-Emission Tomography Predictive Value of Tests Prospective Studies Psoriasis Radiopharmaceuticals Severity of Illness Index Tomography X-Ray Computed
Addictions NeuroImaging Assessment (ANIA)
Valerie Voon, Erica Grodin, Alekhya Mandali, Laurel Morris, Nuria Doñamayor, Kathrin Weidacker, Laura Kwako, David Goldman, George F Koob, Reza Momenan
Apr 15, 2020
Alcohol misuse and addiction are major international public health issues. Addiction can be characterized as a disorder of aberrant neurocircuitry interacting with environmental, genetic and social factors. Neuroimaging in...
Imaging biomarkers in neurodegeneration
Peter NE Young, Mar Estarellas, Emma Coomans, Meera Srikrishna, Helen Beaumont, Anne Maass, Ashwin V Venkataraman, Rikki Lissaman, Daniel Jiménez, Matthew J Betts, Eimear McGlinchey, David Berron, Antoinette O'Connor, Nick C Fox, Joana B Pereira, William Jagust, Stephen F Carter, Ross W Paterson, Michael Schöll
Jun 26, 2020
There is an increasing role for biological markers (biomarkers) in the understanding and diagnosis of neurodegenerative disorders. The application of imaging biomarkers specifically for the in vivo investigation of...
Advances in PET to assess pulmonary inflammation
Laurence Vass, Marie Fisk, Sarah Lee, Frederick J Wilson, Joseph Cheriyan, Ian Wilkinson
Jul 16, 2020
Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand 18F-GE-180 and comparison with 18F-FDG and DCE-MRI.
Marius de Groot, Neel Patel, Roido Manavaki, Robert L Janiczek, Mats Bergstrom, Andrew Östör, Danielle Gerlag, Alexandra Roberts, Martin J Graves, Yakshitha Karkera, Disala Fernando, Prafull Mistry, Adam Walker, Nicolas Wisniacki, Tim D Fryer, Pilar Jimenez-Royo
Jan 27, 2020
PURPOSE:While the aetiology of rheumatoid arthritis (RA) remains unclear, many of the inflammatory components are well characterised. For diagnosis and therapy evaluation, in vivo insight into these processes would be valuable....
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