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The antidiabetic drug lobeglitazone has the potential to inhibit PTP1B activity.
Ruth F Rocha, Tiago Rodrigues, Angela CO Menegatti, Gonçalo JL Bernardes, Hernán Terenzi
May 12, 2020
Protein tyrosine phosphatase 1B (PTP1B) is considered a potential therapeutic target for the treatment of type 2 diabetes mellitus (T2DM), since this enzyme plays a significant role to down-regulate insulin and leptin signalling...