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Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs.
HA King, LC Cobbold, X Pichon, T Pöyry, LA Wilson, H Booden, R Jukes-Jones, K Cain, KS Lilley, M Bushell, AE Willis
Mar 11, 2020
Post-transcriptional control of gene expression is mediated by the interaction of RNA-binding proteins with their cognate mRNAs that specifically regulate their stability, localization and translation. mRNA-binding proteins are...
Apoptosis Cell Nucleus Cyclin T DNA-Binding Proteins HeLa Cells Histone-Lysine N-Methyltransferase Humans MCF-7 Cells Nuclear Matrix-Associated Proteins Octamer Transcription Factors PTB-Associated Splicing Factor Polypyrimidine Tract-Binding Protein RNA Interference RNA Messenger RNA Small Interfering RNA-Binding Proteins TNF-Related Apoptosis-Inducing Ligand Y-Box-Binding Protein 1