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Stem cell niche organization in the Drosophila ovary requires the ECM component Perlecan.
Alfonsa Díaz-Torres
,
Alicia E Rosales-Nieves
,
John R Pearson
,
Carmen Santa-Cruz Mateos
,
Miriam Marín-Menguiano
,
Owen J Marshall
,
Andrea H Brand
,
Acaimo González-Reyes
Jan 28, 2021
Stem cells reside in specialized microenvironments or niches that balance stem cell proliferation and differentiation.1,2 The extracellular matrix (ECM) is an essential component of most niches, because it controls niche...
Drosophila oogenesis
ECM
Perlecan
Adult stem cells
germline stem cells
ovarian niche
Animals
Drosophila
Drosophila Proteins
Drosophila melanogaster
Female
Heparan Sulfate Proteoglycans
Ligands
Ovary
Stem Cell Niche
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