Search
Results: 155
Quantification of Lung PET Images
Tau pathology in early Alzheimer's disease is linked to selective disruptions in neurophysiological network dynamics.
Ece Kocagoncu, Andrew Quinn, Azadeh Firouzian, Elisa Cooper, Andrea Greve, Roger Gunn, Gary Green, Mark W Woolrich, Richard N Henson, Simon Lovestone, Deep and Frequent Phenotyping study team, James B Rowe
Mar 12, 2020
Understanding the role of Tau protein aggregation in the pathogenesis of Alzheimer's disease is critical for the development of new Tau-based therapeutic strategies to slow or prevent dementia. We tested the hypothesis that Tau...
Alzheimer's Disease Connectivity Graph theory MEG PET Tau Aged Aged 80 and over Alzheimer Disease Cognition Female Humans Magnetoencephalography Male Middle Aged Molecular Imaging Occipital Lobe Parietal Lobe Positron-Emission Tomography protein aggregation Pathological Synaptic Transmission tau Proteins
The neurochemical substrates of habitual and goal-directed control.
Valerie Voon, Juho Joutsa, Joonas Majuri, Kwangyeol Baek, Camilla L Nord, Eveliina Arponen, Sarita Forsback, Valtteri Kaasinen
Nov 28, 2019
Our daily decisions are governed by the arbitration between goal-directed and habitual strategies. However, the neurochemical basis of this arbitration is unclear. We assessed the contribution of dopaminergic, serotonergic, and...
Imaging tumour hypoxia with positron emission tomography.
IN Fleming, R Manavaki, PJ Blower, C West, KJ Williams, AL Harris, J Domarkas, S Lord, C Baldry, FJ Gilbert
Jan 12, 2015
An unusual finding in a 57-year-old woman with new onset hypertension and a diastolic murmur.
CLINICAL INTRODUCTION: A 57-year-old woman presented to our clinic with breathlessness brought on while walking uphill. She had been recently diagnosed with systemic hypertension. There was no known family history of cardiac...
Computed Tomography Angiography Coronary Aneurysm Coronary Angiography Echocardiography Female Fluorodeoxyglucose F18 Heart Murmurs Hemodynamics Humans Hypertension Magnetic Resonance Imaging Middle Aged Multimodal Imaging Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Takayasu arteritis
Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease
MJ Firbank, AJ Yarnall, RA Lawson, GW Duncan, TK Khoo, GS Petrides, JT O'Brien, RA Barker, RJ Maxwell, DJ Brooks, DJ Burn
Oct 14, 2016
High Structural Stress and Presence of Intraluminal Thrombus Predict Abdominal Aortic Aneurysm 18F-FDG Uptake
Yuan Huang, Zhongzhao Teng, Maysoon Elkhawad, Jason M Tarkin, Nikhil Joshi, Jonathan R Boyle, John R Buscombe, Timothy D Fryer, Yongxue Zhang, Ah Yeon Park, Ian B Wilkinson, David E Newby, Jonathan H Gillard, James HF Rudd
Nov 10, 2016
abdominal aortic aneurysm Fluorodeoxyglucose F18 Inflammation mechanical stress Positron-Emission Tomography Thrombosis Aged Aged 80 and over Aorta Abdominal Aortic Aneurysm Abdominal Aortic Rupture Aortitis Aortography Biomechanical Phenomena Computed Tomography Angiography Female Finite element analysis Fluorodeoxyglucose F18 Humans Linear Models Male Middle Aged Multivariate Analysis Positron Emission Tomography Computed Tomography Predictive Value of Tests Prognosis Pulsatile Flow Radiographic Image Interpretation Computer-Assisted Radiopharmaceuticals Regional Blood Flow Risk Factors Stress Mechanical Thrombosis Vascular Calcification
Thresholds for Arterial Wall Inflammation Quantified by 18F-FDG PET Imaging
Fleur M van der Valk, Simone L Verweij, Koos AH Zwinderman, Aart C Strang, Yannick Kaiser, Henk A Marquering, Aart J Nederveen, Erik SG Stroes, Hein J Verberne, James HF Rudd
May 05, 2016
(18)F-FDG PET/CT Atherosclerosis Imaging Inflammation thresholds Aged Aorta Aortitis Arteritis Carotid Arteries Carotid Artery Diseases Case-Control Studies Female Fluorodeoxyglucose F18 Humans Male Middle Aged Observer Variation Plaque Atherosclerotic Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Reproducibility of Results
PET Reconstruction With an Anatomical MRI Prior Using Parallel Level Sets.
Matthias J Ehrhardt, Pawel Markiewicz, Maria Liljeroth, Anna Barnes, Ville Kolehmainen, John S Duncan, Luis Pizarro, David Atkinson, Brian F Hutton, Sebastien Ourselin, Kris Thielemans, Simon R Arridge
May 10, 2016
Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury.
Tonny V Veenith, Eleanor L Carter, Thomas Geeraerts, Julia Grossac, Virginia FJ Newcombe, Joanne Outtrim, Gloria S Gee, Victoria Lupson, Rob Smith, Franklin I Aigbirhio, Tim D Fryer, Young T Hong, David K Menon, Jonathan P Coles
Mar 30, 2016
A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention
Natalia del Campo, Tim D Fryer, Young T Hong, Rob Smith, Laurent Brichard, Julio Acosta-Cabronero, Samuel R Chamberlain, Roger Tait, David Izquierdo, Ralf Regenthal, Jonathan Dowson, John Suckling, Jean-Claude Baron, Franklin I Aigbirhio, Trevor W Robbins, Barbara J Sahakian, Ulrich Müller
Aug 19, 2020
Through the combined use of (18)F-fallypride positron emission tomography and magnetic resonance imaging this study examined the neural mechanisms underlying the attentional deficits associated with attention...
18F-fallypride PET Attention deficit/hyperactivity disorder Dopamine methylphenidate sustained attention Adult Attention Deficit Disorder with Hyperactivity Benzamides Corpus Striatum Cross-Over Studies Dopamine Uptake Inhibitors Double-Blind Method Fluorodeoxyglucose F18 Humans Magnetic Resonance Imaging Male Mesencephalon methylphenidate Multimodal Imaging Positron-Emission Tomography Psychiatric Status Rating Scales Radiopharmaceuticals Young Adult
Published by: Brain
Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity.
Liam R Wilson, Deniz Vatansever, Tiina Annus, Guy B Williams, Young T Hong, Tim D Fryer, Peter J Nestor, Anthony J Holland, Shahid H Zaman
Jul 10, 2019
Down's syndrome is a chromosomal disorder that invariably results in both intellectual disability and Alzheimer's disease neuropathology. However, only a limited number of studies to date have investigated intrinsic brain...
Alzheimer's Disease Down's syndrome anti-correlation Default mode network functional connectivity Memory Adult Alzheimer Disease Amyloid Aniline Compounds Carbon Radioisotopes Cerebral Cortex Connectome Cross-Sectional Studies Down Syndrome Female Humans Magnetic Resonance Imaging Male Middle Aged Positron-Emission Tomography Radiopharmaceuticals Thiazoles
In vivo 18F-flortaucipir PET does not accurately support the staging of progressive supranuclear palsy
Maura Malpetti, Sanne Kaalund, Kamen Tsvetanov, Timothy Rittman, Mayen Briggs, Kieren SJ Allinson, Luca Passamonti, Negin Holland, P Simon Jones, Tim Fryer, Young Hong, Antonina Kouli, W Richard Bevan-Jones, Elijah Mak, George Savulich, Maria Grazia Spillantini, Franklin I Aigbirhio, Caroline Williams-Gray, John T O'Brien, James B Rowe
Oct 12, 2021
Novel Approach for Assessing Postinfarct Myocardial Injury and Inflammation Using Hybrid Somatostatin Receptor Positron Emission Tomography/Magnetic Resonance Imaging.
Andrej Ćorović, Deepa Gopalan, Christopher Wall, Marta Peverelli, Stephen P Hoole, Patrick A Calvert, Roido Manavaki, Tim D Fryer, Luigi Aloj, Martin J Graves, Martin R Bennett, James HF Rudd, Jason M Tarkin
Feb 17, 2023
Post-infarct inflammation and its resolution modulate ischemic injury after myocardial infarction (MI). While cardiac magnetic resonance imaging (MRI) is useful for assessing ventricular function, viability and structural...
The pattern of amyloid accumulation in the brains of adults with Down syndrome.
Tiina Annus, Liam R Wilson, Young T Hong, Julio Acosta-Cabronero, Tim D Fryer, Arturo Cardenas-Blanco, Robert Smith, Istvan Boros, Jonathan P Coles, Franklin I Aigbirhio, David K Menon, Shahid H Zaman, Peter J Nestor, Anthony J Holland
Aug 18, 2015
Imaging Atherosclerosis.
Jason M Tarkin, Marc R Dweck, Nicholas R Evans, Richard AP Takx, Adam J Brown, Ahmed Tawakol, Zahi A Fayad, James HF Rudd
Dec 23, 2015
Atherosclerosis Coronary Artery Disease Molecular Imaging Multimodal Imaging Risk Factors Coronary Angiography Coronary Artery Disease Coronary Vessels Diagnostic Imaging Humans Magnetic Resonance Angiography Multimodal Imaging Plaque Atherosclerotic Positron-Emission Tomography Predictive Value of Tests Prognosis Risk Assessment Risk Factors Severity of Illness Index Tomography Emission-Computed Single-Photon Tomography Optical Coherence Tomography X-Ray Computed Ultrasonography Interventional
Neural correlates of the severity of cocaine, heroin, alcohol, MDMA and cannabis use in polysubstance abusers
Laura Moreno-López, Emmanuel A Stamatakis, Maria José Fernández-Serrano, Manuel Gómez-Río, Antonio Rodríguez-Fernández, Miguel Pérez-García, Antonio Verdejo-García
Aug 08, 2017
INTRODUCTION: Functional imaging studies of addiction following protracted abstinence have not been systematically conducted to look at the associations between severity of use of different drugs and brain dysfunction. Findings...
Magnetic resonance imaging and positron emission tomography in anti-NMDA receptor encephalitis
Due to a variety of clinical manifestations anti-N-methyl-d-aspartate (NMDA) receptor encephalitis may be difficult to diagnose. Magnetic resonance imaging (MRI) may be used as a component of the workup for encephalopathy....
Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury.
Young T Hong, Tonny Veenith, Deborah Dewar, Joanne G Outtrim, Vaithianadan Mani, Claire Williams, Sally Pimlott, Peter JA Hutchinson, Adriana Tavares, Roberto Canales, Chester A Mathis, William E Klunk, Franklin I Aigbirhio, Jonathan P Coles, Jean-Claude Baron, John D Pickard, Tim D Fryer, William Stewart, David K Menon
Jun 18, 2018
OBJECTIVES: To image amyloid deposition in patients with traumatic brain injury (TBI) using carbon 11-labeled Pittsburgh Compound B ([11C]PiB) positron emission tomography (PET) and to validate these findings using...
Neuroinflammation in Neurodegenerative Diseases
Marco Aiello, Carlo Cavaliere, Dario Fiorenza, Andrea Duggento, Luca Passamonti, Nicola Toschi
Nov 07, 2018
Positron emission tomography (PET) provides spatially localized information about brain metabolism and function and innovative tracers have extended this potential to the study of neuroinflammation (NI), an important process in...
Beta amyloid deposition maps onto hippocampal and subiculum atrophy in dementia with Lewy bodies.
Elijah Mak, Paul C Donaghy, Elizabeth McKiernan, Michael J Firbank, Jim Lloyd, George S Petrides, Alan J Thomas, John T O'Brien
Nov 30, 2018
Novel Approach to Imaging Active Takayasu Arteritis Using Somatostatin Receptor Positron Emission Tomography/Magnetic Resonance Imaging.
Jason M Tarkin, Christopher Wall, Deepa Gopalan, Luigi Aloj, Roido Manavaki, Tim D Fryer, Eric O Aboagye, Martin R Bennett, James E Peters, James HF Rudd, Justin C Mason
Jan 08, 2020
Takayasu arteritis Aortic Diseases Molecular Imaging positron emission tomography Vasculitis Adult Aorta Biomarkers Female Fluorodeoxyglucose F18 Glucocorticoids Humans Immunosuppressive Agents Magnetic Resonance Imaging Middle Aged Molecular Imaging Organometallic Compounds Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Receptors Somatostatin Takotsubo cardiomyopathy Treatment Outcome
Magnetic Resonance Imaging Is More Sensitive Than PET for Detecting Treatment-Induced Cell Death-Dependent Changes in Glycolysis.
Richard L Hesketh, Jiazheng Wang, Alan J Wright, David Y Lewis, Alice E Denton, Richard Grenfell, Jodi L Miller, Robert Bielik, Marcel Gehrung, Maria Fala, Susana Ros, Bangwen Xie, De-En Hu, Kevin M Brindle
May 17, 2019
Metabolic imaging has been widely used to measure the early responses of tumors to treatment. Here, we assess the abilities of PET measurement of [18F]FDG uptake and MRI measurement of hyperpolarized [1-13C]pyruvate metabolism...
Adenocarcinoma Animals Antineoplastic Agents Carbon Isotopes Cell Death Cell Line Tumor Colorectal Neoplasms Female Fluorodeoxyglucose F18 Glycolysis Heterografts Humans Lactic Acid Magnetic Resonance Imaging Mice Inbred BALB C Mice Nude Positron-Emission Tomography Pyruvic Acid Radiopharmaceuticals Receptors TNF-Related Apoptosis-Inducing Ligand Triple Negative Breast Neoplasms
68Ga-DOTATATE PET Identifies Residual Myocardial Inflammation and Bone Marrow Activation After Myocardial Infarction.
Jason M Tarkin, Claudia Calcagno, Marc R Dweck, Nicholas R Evans, Mohammed M Chowdhury, Deepa Gopalan, David E Newby, Zahi A Fayad, Martin R Bennett, James HF Rudd
Mar 04, 2019
Myocardial infarction (MI) healing occurs in two phases: first an inflammatory phase, where clearance of necrotic debris occurs, followed by a reparative phase characterized by angiogenesis, granulation tissue formation and...
Imaging unstable plaque.
Rouchelle S Sriranjan, Jason M Tarkin, Nicholas R Evans, Mohammed M Chowdhury, James H Rudd
Mar 28, 2019
Recent advances in imaging technology have enabled us to utilise a range of diagnostic approaches to better characterise high-risk atherosclerotic plaque. The aim of this article is to review current and emerging techniques used...
Animals arteries Calcinosis Cardiovascular Diseases Coronary Angiography Fluorodeoxyglucose F18 Humans Hypoxia Inflammation Magnetic Resonance Imaging Mice Molecular Probes Neovascularization Pathologic Plaque Atherosclerotic Positron-Emission Tomography risk Tomography Emission-Computed Single-Photon Tomography X-Ray Computed Ultrasonography Interventional
Published by: Q J Nucl Med Mol Imaging
|
|< |
< |
1 |