Search
Results: 3
The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.
Jingwei Sim, Andrew S Cowburn, Asis Palazon, Basetti Madhu, Petros A Tyrakis, David Macías, David M Bargiela, Sandra Pietsch, Michael Gralla, Colin E Evans, Thaksaon Kittipassorn, Yu CJ Chey, Cristina M Branco, Helene Rundqvist, Daniel J Peet, Randall S Johnson
Apr 10, 2018
Animals require an immediate response to oxygen availability to allow rapid shifts between oxidative and glycolytic metabolism. These metabolic shifts are highly regulated by the HIF transcription factor. The factor inhibiting...
HIF Hypoxia metabolism Adaptation Physiological Animals Cell Hypoxia Gene Expression Regulation Glycolysis Hypoxia-Inducible Factor-Proline Dioxygenases Male Mice Mice Inbred C57BL Mixed Function Oxygenases Oxygen Oxygen Consumption Procollagen-Proline Dioxygenase Signal Transduction Transcription Genetic Von Hippel-Lindau Tumor Suppressor Protein
Regulation of nerve growth and patterning by cell surface protein disulphide isomerase.
Geoffrey MW Cook, Catia Sousa, Julia Schaeffer, Katherine Wiles, Prem Jareonsettasin, Asanish Kalyanasundaram, Eleanor Walder, Catharina Casper, Serena Patel, Pei Wei Chua, Gioia Riboni-Verri, Mansoor Raza, Nol Swaddiwudhipong, Andrew Hui, Ameer Abdullah, Saj Wajed, Roger J Keynes
Aug 19, 2020
Contact repulsion of growing axons is an essential mechanism for spinal nerve patterning. In birds and mammals the embryonic somites generate a linear series of impenetrable barriers, forcing axon growth cones to traverse one...
Axon guidance chicken developmental biology human neuroscience rat repeat patterning somite Spinal nerve Animals Astrocytes Axon guidance Cell Line Chick Embryo Chickens developmental biology Gene Knockdown Techniques Growth Cones Humans Membrane Proteins Neurosciences Nitric oxide Procollagen-Proline Dioxygenase Protein Disulfide-Isomerases Rats Signal Transduction Somites Spinal Nerves
Mannose binding lectin is hydroxylated by collagen prolyl-4-hydroxylase and inhibited by some PHD inhibitors
FG-4592 HEK293 Cells PHD inhibitors chronic kidney disease collagen prolyl-4-hydroxylase hypoxia inducible factor mannose binding lectin post-translational Protein Processing renal anemia vadadustat molidustat Collagen Hypoxia-Inducible Factor-Proline Dioxygenases Procollagen-Proline Dioxygenase Prolyl Hydroxylases Prolyl-Hydroxylase Inhibitors