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Results: 4

A Touchscreen Motivation Assessment Evaluated in Huntington's Disease Patients and R6/1 Model Mice.

Christopher J Heath, Claire O'Callaghan, Sarah L Mason, Benjamin U Phillips, Lisa M Saksida, Trevor W Robbins, Roger A Barker, Timothy J Bussey, Barbara J Sahakian

Jul 30, 2019

Huntington's disease Apathy motivation Progressive ratio Touchscreen Translational

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Oxygen responses within the nucleus accumbens are associated with individual differences in effort exertion in rats.

Jonathan M Hailwood, Gary Gilmour, Trevor W Robbins, Lisa M Saksida, Timothy J Bussey, Hugh M Marston, Francois Gastambide

Nov 16, 2018

Goal-directed motivated behaviour is crucial for everyday life. Such behaviour is often measured, in rodents, under a progressive ratio (PR) schedule of reinforcement. Previous studies have identified a few brain structures...

motivation orbitofrontal cortex oxygen amperometry Progressive ratio Animals Electrodes Implanted Male motivation Nucleus Accumbens Oxygen Oxygen Consumption Physical Exertion Rats Rats Wistar Reinforcement Schedule Reward

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Optimisation of cognitive performance in rodent operant (touchscreen) testing

BU Phillips, CJ Heath, Z Ossowska, TJ Bussey, LM Saksida

Apr 12, 2017

Touchscreen MOUSE Progressive ratio fixed ratio rate analysis reinforcer

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Cover Image for Motivational assessment of mice using the touchscreen operant testing system

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