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Results: 40
Clinical, socio-demographic and psychological characteristics in individuals with persistent psychotic experiences with and without a "need for care"
Emmanuelle Roisin Peters, Thomas Ward, Mike Jackson, Craig Morgan, Monica Charalambides, Philip McGuire, Peter Woodruff, Pamela Charlotte Jacobsen, Paul Chadwick, Philippa Anne Garety
Feb 01, 2016
Individuals reporting persistent psychotic experiences (PEs) in the general population, but without a “need for care”, are a unique group of particular importance in identifying risk and protective factors for psychosis. We...
Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids.
Katherine E Beaney, Jackie A Cooper, Stela McLachlan, S Goya Wannamethee, Barbara J Jefferis, Peter Whincup, Yoav Ben-Shlomo, Jacqueline F Price, Meena Kumari, Andrew Wong, Ken Ong, Rebecca Hardy, Diana Kuh, Mika Kivimaki, Antti J Kangas, Pasi Soininen, Mika Ala-Korpela, Fotios Drenos, Steve E Humphries, UCLEB Consortium
Sep 29, 2016
AIMS: An intergenic locus on chromosome 1 (lead SNP rs10911021) was previously associated with coronary heart disease (CHD) in type 2 diabetes (T2D). Using data from the UCLEB consortium we investigated the relationship between...
coronary heart disease genetic risk HDL-cholesterol Metabolomics Aged Amino Acids Biomarkers Cholesterol HDL Chromosomes Human Pair 1 Coronary Disease DNA Intergenic Diabetes mellitus Type 2 Down-Regulation Female Gene Frequency Genetic Association Studies Genetic Predisposition to Disease High-Throughput Screening Assays Humans Magnetic Resonance Spectroscopy Male Metabolomics Middle Aged Particle Size Phenotype Polymorphism Single Nucleotide Protective factors Risk Assessment Risk Factors
Impact of Healthy Lifestyle Factors on Life Expectancies in the US Population.
Yanping Li, An Pan, Dong D Wang, Xiaoran Liu, Klodian Dhana, Oscar H Franco, Stephen Kaptoge, Emanuele Di Angelantonio, Meir Stampfer, Walter C Willett, Frank B Hu
May 16, 2018
BACKGROUND: Americans have a shorter life expectancy compared with residents of almost all other high-income countries. We aim to estimate the impact of lifestyle factors on premature mortality and life expectancy in the US...
Healthy lifestyle Life Expectancy Mortality Premature Adult Aged Aged 80 and over Alcohol Drinking Body Mass Index Cause of Death Databases Factual Diet Healthy Exercise Female Health Personnel health status Healthy lifestyle Humans Life Expectancy Male Middle Aged Non-Smokers Nurses Nutrition Surveys Protective factors Risk Factors Risk Reduction Behavior Time Factors United States
Temporal Trends in Maternal Food Intake Frequencies and Associations with Gestational Diabetes
Diet Food frequency questionnaire Glucose Insulin Secretion Pregnancy Adult Biomarkers Blood Glucose Diabetes Gestational Diet Eating Eggs England Feeding Behavior Female Humans Incidence Insulin Longitudinal Studies Maternal Nutritional Physiological Phenomena Nutritional Status Pregnancy Prospective Studies Protective factors Risk Assessment Risk Factors Time Factors
Plasma Phospholipid Fatty Acids, FADS1 and Risk of 15 Cardiovascular Diseases
Shuai Yuan, Magnus Bäck, Maria Bruzelius, Amy M Mason, Stephen Burgess, Susanna Larsson
Dec 11, 2019
?5-desaturase FADS Mendelian randomisation cardiovascular disease Diet Fatty Acids Alleles Arachidonic Acid Cardiovascular Diseases Data analysis Delta-5 Fatty Acid Desaturase Fatty Acid Desaturases Fatty Acids Genetic Predisposition to Disease Humans Linoleic Acid Mendelian Randomization Analysis Odds Ratio Oleic Acid Phospholipids Polymorphism Single Nucleotide Protective factors Risk Factors Stearic Acids alpha-Linolenic Acid
Consumption of Meat, Fish, Dairy Products, and Eggs and Risk of Ischemic Heart Disease.
Timothy J Key, Paul N Appleby, Kathryn E Bradbury, Michael Sweeting, Angela Wood, Ingegerd Johansson, Tilman Kühn, Marinka Steur, Elisabete Weiderpass, Maria Wennberg, Anne Mette Lund Würtz, Antonio Agudo, Jonas Andersson, Larraitz Arriola, Heiner Boeing, Jolanda MA Boer, Fabrice Bonnet, Marie-Christine Boutron-Ruault, Amanda J Cross, Ulrika Ericson, Guy Fagherazzi, Pietro Ferrari, Marc Gunter, José María Huerta, Verena Katzke, Kay-Tee Khaw, Vittorio Krogh, Carlo La Vecchia, Giuseppe Matullo, Conchi Moreno-Iribas, Androniki Naska, Lena Maria Nilsson, Anja Olsen, Kim Overvad, Domenico Palli, Salvatore Panico, Elena Molina-Portillo, J Ramón Quirós, Guri Skeie, Ivonne Sluijs, Emily Sonestedt, Magdalena Stepien, Anne Tjønneland, Antonia Trichopoulou, Rosario Tumino, Ioanna Tzoulaki, Yvonne T van der Schouw, WM Monique Verschuren, Emanuele Di Angelantonio, Claudia Langenberg, Nita Forouhi, Nick Wareham, Adam Butterworth, Elio Riboli, John Danesh
Apr 05, 2019
dairy products Eggs fish Heart Diseases Meat Adult Aged Biomarkers blood pressure Cholesterol HDL Cross-Sectional Studies dairy products Diet Surveys Diet Healthy Eggs Europe Female Humans Male Meat Middle Aged Myocardial Ischemia Nutritive Value Prospective Studies Protective factors Recommended Dietary Allowances Risk Assessment Risk Factors Risk Reduction Behavior seafood Time Factors
No robust evidence for an interaction between early-life adversity and protective factors on global and regional brain volumes.
Andrea P Cortes Hidalgo, Henning Tiemeier, Stephen A Metcalf, Maximilian Monninger, Andreas Meyer-Lindenberg, Pascal-M Aggensteiner, Marian J Bakermans-Kranenburg, Tonya White, Tobias Banaschewski, Marinus H van IJzendoorn, Nathalie E Holz
Dec 08, 2022
Childhood adversity is associated with brain morphology and poor psychological outcomes, and evidence of protective factors counteracting childhood adversity effects on neurobiology is scarce. We examined the interplay of...
Clinical, socio-demographic and psychological characteristics in individuals with persistent psychotic experiences with and without a "need for care"
Emmanuelle Roisin Peters, Thomas Ward, Mike Jackson, Craig Morgan, Monica Charalambides, Philip McGuire, Peter Woodruff, Pamela Charlotte Jacobsen, Paul Chadwick, Philippa Anne Garety
Feb 01, 2016
Individuals reporting persistent psychotic experiences (PEs) in the general population, but without a “need for care”, are a unique group of particular importance in identifying risk and protective factors for psychosis. We...
A cross-cultural exploration of children's perceptions of wellbeing
There is a growing body of literature on children's wellbeing. However, historically, focus has been on adults’ perspectives, leading to adult-centric views of wellbeing. Although recent years have witnessed an increase in...
A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Neil Murphy, Amanda J Cross, Mustapha Abubakar, Mazda Jenab, Krasimira Aleksandrova, Marie-Christine Boutron-Ruault, Laure Dossus, Antoine Racine, Tilman Kühn, Verena A Katzke, Anne Tjønneland, Kristina En Petersen, Kim Overvad, J Ramón Quirós, Paula Jakszyn, Esther Molina-Montes, Miren Dorronsoro, José-María Huerta, Aurelio Barricarte, Kay-Tee Khaw, Nick Wareham, Ruth C Travis, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Giovanna Masala, Vittorio Krogh, Rosario Tumino, Paolo Vineis, Salvatore Panico, H Bas Bueno-De-Mesquita, Peter D Siersema, Petra H Peeters, Bodil Ohlsson, Ulrika Ericson, Richard Palmqvist, Hanna Nyström, Elisabete Weiderpass, Guri Skeie, Heinz Freisling, So Yeon Kong, Kostas Tsilidis, David C Muller, Elio Riboli, Marc J Gunter
Nov 08, 2018
BACKGROUND: Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals...
Adiposity Biomarkers Body Mass Index Body Size C-Peptide Case-Control Studies Chi-Square Distribution Colorectal Neoplasms Europe Female health status Humans Hyperinsulinism Incidence Logistic Models Male Middle Aged Multivariate Analysis obesity obesity Metabolically Benign Odds Ratio Phenotype Prospective Studies Protective factors Risk Assessment Risk Factors Waist Circumference
Investigation of correlates of protection against pharyngeal carriage of Neisseria meningitidis genogroups W and Y in the African meningitis belt
LV Cooper, RM Boukary, R Borrow, A Aseffa, W Mihret, JM Collard, D Doumagoum, A Hodgson, C Sokhna, B Omotar, S Sow, SL Quaye, K Diallo, O Manigart, MCJ Maiden, H Findlow, R Borrow, JM Stuart, BM Greenwood, CL Trotter
Sep 26, 2017
Risk and protective factors for mental disorders beyond genetics
Celso Arango, Elena Dragioti, Marco Solmi, Samuele Cortese, Katharina Domschke, Robin M Murray, Peter B Jones, Rudolf Uher, Andre F Carvalho, Abraham Reichenberg, Jae Ii Shin, Ole A Andreassen, Christoph U Correll, Paolo Fusar-Poli
Apr 15, 2021
Decades of research have revealed numerous risk factors for mental disorders beyond genetics, but their consistency and magnitude remain uncer-tain. We conducted a "meta-umbrella" systematic synthesis of umbrella reviews, which...
Antenatal Exposure to UV-B Radiation and Preeclampsia
Claire E Hastie, Daniel F Mackay, Tom L Clemens, Mark PC Cherrie, Lauren J Megaw, Gordon CS Smith, Sarah J Stock, Chris Dibben, Jill P Pell
May 24, 2021
Lifelong bilingualism and mechanisms of neuroprotection in Alzheimer dementia.
Arianna Sala, Maura Malpetti, Mohsen Farsad, Francesca Lubian, Giuseppe Magnani, Giulia Frasca Polara, Jean-Benoit Epiney, Jubin Abutalebi, Frédéric Assal, Valentina Garibotto, Daniela Perani
Nov 03, 2021
Lifelong bilingualism is associated with delayed dementia onset, suggesting a protective effect on the brain. Here, we aim to study the effects of lifelong bilingualism as a dichotomous and continuous phenomenon, on brain...
Infant regulatory function acts as a protective factor for later traits of autism spectrum disorder and attention deficit/hyperactivity disorder but not callous unemotional traits.
Rachael Bedford, Teodora Gliga, Alexandra Hendry, Emily JH Jones, Greg Pasco, Tony Charman, Mark H Johnson, Andrew Pickles, BASIS Team
Jul 17, 2019
BACKGROUND: Reduced executive functions (EF) are commonly associated with developmental conditions (e.g., autism spectrum disorder, ASD; attention deficit/hyperactivity disorder, ADHD), although EF seems to be typical in...
Attention deficit/hyperactivity disorder Autism spectrum disorder Callous unemotional traits Executive Function Infants at risk Regulatory function Attention Deficit Disorder with Hyperactivity Autism spectrum disorder Child Child Preschool Conduct Disorder Executive Function Female Genetic Predisposition to Disease Humans Infant Longitudinal Studies Male Protective factors self-control
Exploring causality of the association between smoking and Parkinson's disease.
Valentina Gallo, Paolo Vineis, Mariagrazia Cancellieri, Paolo Chiodini, Roger A Barker, Carol Brayne, Neil Pearce, Roel Vermeulen, Salvatore Panico, Bas Bueno-de-Mesquita, Nicola Vanacore, Lars Forsgren, Silvia Ramat, Eva Ardanaz, Larraitz Arriola, Jesper Peterson, Oskar Hansson, Diana Gavrila, Carlotta Sacerdote, Sabina Sieri, Tilman Kühn, Verena A Katzke, Yvonne T van der Schouw, Andreas Kyrozis, Giovanna Masala, Amalia Mattiello, Robert Perneczky, Lefkos Middleton, Rodolfo Saracci, Elio Riboli
Dec 11, 2018
Laboratory-Assessed Markers of Cardiometabolic Health and Associations with GIS-Based Measures of Active-Living Environments.
Active-living-friendly environments have been linked to physical activity, but their relationships with specific markers of cardiometabolic health remain unclear. We estimated the associations between active-living environments...
blood pressure body-mass index cardiometabolic health neighborhood physical-activity environments physical activity Biomarkers Canada Cardiovascular Diseases Cross-Sectional Studies Exercise Female Geographic Information Systems Health Surveys Humans Male Metabolic Diseases Middle Aged Protective factors Residence Characteristics Risk Factors
Examining the efficacy of video-based micro-interventions for improving risk and protective factors for disordered eating among young adult women
Brief self-guided activities designed for focused and immediate benefits, termed micro-interventions, have the potential to aid reach and engagement in mental health interventions; however further validation is needed. This...
Body Image Cognitive dissonance Early intervention Feeding and Eating Disorders media exposure microintervention Mindfulness Prevention Protective factors Risk Factors /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
The role of physical activity in the development of first cardiovascular disease event
Hanan Amadid, Nanna B Johansen, Anne-Louise Bjerregaard, Søren Brage, Kristine Færch, Torsten Lauritzen, Daniel R Witte, Annelli Sandbæk, Marit E Jørgensen, Dorte Vistisen
Nov 16, 2018
cardiovascular disease Objective physical activity Prospective cohort study Tree-structured survival analysis Type 2 diabetes Aged Cardiovascular Diseases Denmark Exercise Female Healthy lifestyle Humans Male Middle Aged Prognosis Prospective Studies Protective factors Risk Assessment Risk Factors Risk Reduction Behavior Sedentary Behavior Time Factors
Stroke Prevention Rehabilitation Intervention Trial of Exercise (SPRITE) - a randomised feasibility study.
Neil Heron, Frank Kee, Jonathan Mant, Philip M Reilly, Margaret Cupples, Mark Tully, Michael Donnelly
Feb 09, 2018
Background
The value of cardiac rehabilitation (CR) after a transient ischaemic attack (TIA) or minor stroke is untested despite these conditions sharing similar pathology and risk factors to coronary heart disease. We aimed to...
Humans Ischemic Attack Transient Recurrence Treatment Outcome Exercise Therapy Risk Factors Feasibility Studies Health Knowledge Attitudes practice Patient Compliance motivation Recovery of Function Time Factors social support Aged Middle Aged Home Care Services Hospital-Based Northern Ireland Female Male Manuals as Topic Patient Education as Topic stroke Secondary Prevention Actigraphy Protective factors Stroke Rehabilitation Fitness Trackers
Adverse childhood experiences (ACEs) and later-life depression
OBJECTIVE: To investigate associations between adverse childhood experiences (ACEs) and later-life depressive symptoms; and to explore whether perceived social support (PSS) moderates these. METHOD: We analysed baseline data...
adverse childhood experience depression and mood disorders Mental Health Adolescent Adult Survivors of Child Abuse Aged Child Child Abuse Child Preschool Cohort Studies Depression Depressive Disorder Family Characteristics Family Relations Humans Ireland Life Change Events Logistic Models Middle Aged Perception Protective factors Self Report social support Surveys and Questionnaires
Polymorphism in killer cell immunoglobulin-like receptors and human leukocyte antigen-c and predisposition to preeclampsia in Ethiopian pregnant women population.
Tsehayneh Kelemu, Lena Erlandsson, Daniel Seifu, Eva Hansson, Markos Abebe, Sisay Teklu, Selfu Girma, James A Traherne, Ashley Moffett, Stefan R Hansson
Jun 26, 2020
INTRODUCTION: Preeclampsia (PE) is a human specific pregnancy-related syndrome of unknown etiology that affects 2-8 % of pregnancies. Polymorphism in maternal Killer Cell Immunoglobulin-like Receptors (KIRs) and the ligand fetal...
HLA KIR natural killer cell Preeclampsia Trophoblast cell Adolescent Adult Case-Control Studies Ethiopia Female Fetus Gene Frequency Genetic Predisposition to Disease HLA-C Antigens Humans Immune Tolerance Killer Cells Natural Polymorphism Single Nucleotide pre-eclampsia Pregnancy Protective factors Receptors KIR Young Adult
A cross-cultural exploration of children's perceptions of wellbeing
There is a growing body of literature on children's wellbeing. However, historically, focus has been on adults’ perspectives, leading to adult-centric views of wellbeing. Although recent years have witnessed an increase in...
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.
Matti Marklund, Jason HY Wu, Fumiaki Imamura, Liana C Del Gobbo, Amanda Fretts, Janette de Goede, Peilin Shi, Nathan Tintle, Maria Wennberg, Stella Aslibekyan, Tzu-An Chen, Marcia C de Oliveira Otto, Yoichiro Hirakawa, Helle Højmark Eriksen, Janine Kröger, Federica Laguzzi, Maria Lankinen, Rachel A Murphy, Kiesha Prem, Cécilia Samieri, Jyrki Virtanen, Alexis C Wood, Kerry Wong, Wei-Sin Yang, Xia Zhou, Ana Baylin, Jolanda MA Boer, Ingeborg A Brouwer, Hannia Campos, Paulo HM Chaves, Kuo-Liong Chien, Ulf de Faire, Luc Djoussé, Gudny Eiriksdottir, Naglaa El-Abbadi, Nita G Forouhi, J Michael Gaziano, Johanna M Geleijnse, Bruna Gigante, Graham Giles, Eliseo Guallar, Vilmundur Gudnason, Tamara Harris, William S Harris, Catherine Helmer, Mai-Lis Hellenius, Allison Hodge, Frank B Hu, Paul F Jacques, Jan-Håkan Jansson, Anya Kalsbeek, Kay-Tee Khaw, Woon-Puay Koh, Markku Laakso, Karin Leander, Hung-Ju Lin, Lars Lind, Robert Luben, Juhua Luo, Barbara McKnight, Jaakko Mursu, Toshiharu Ninomiya, Kim Overvad, Bruce M Psaty, Eric Rimm, Matthias B Schulze, David Siscovick, Michael Skjelbo Nielsen, Albert V Smith, Brian T Steffen, Lyn Steffen, Qi Sun, Johan Sundström, Michael Y Tsai, Hugh Tunstall-Pedoe, Matti IJ Uusitupa, Rob M van Dam, Jenna Veenstra, WM Monique Verschuren, Nick Wareham, Walter Willett, Mark Woodward, Jian-Min Yuan, Renata Micha, Rozenn N Lemaitre, Dariush Mozaffarian, Ulf Risérus, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCe)
Feb 18, 2019
Arachidonic Acid Biomarkers Cardiovascular Diseases Diet EPIDEMIOLOGY Linoleic Acid Primary Prevention Aged Arachidonic Acid Biomarkers Cardiovascular Diseases Diet Healthy Dietary Fats Female Humans Linoleic Acid Male Middle Aged Nutritive Value Observational Studies as Topic Primary Prevention Protective factors Recommended Dietary Allowances Risk Assessment Risk Factors Risk Reduction Behavior
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