Surfactant protein D is a causal risk factor for COPD
Ma'en Obeidat,
Xuan Li,
Stephen Burgess,
Guohai Zhou,
Nick Fishbane,
Nadia N Hansel,
Yohan Bossé,
Philippe Joubert,
Ke Hao,
David C Nickle,
Maarten van den Berge,
Wim Timens,
Michael H Cho,
Brian D Hobbs,
Kim de Jong,
Marike Boezen,
Rayjean J Hung,
Nicholas Rafaels,
Rasika Mathias,
Ingo Ruczinski,
Terri H Beaty,
Kathleen C Barnes,
Peter D Paré,
Don D Sin,
Lung eQTL Consortium, Lung Health Study International COPD Genetics Consortium
Jul 25, 2018
Surfactant protein D (SP-D) is produced primarily in the lung and is involved in regulating pulmonary surfactants, lipid homeostasis and innate immunity. Circulating SP-D levels in blood are associated with chronic obstructive...