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Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq.
Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems
AG Patterson, SA Jackson, C Taylor, GB Evans, GPC Salmond, R Przybilski, RHJ Staals, PC Fineran
Jan 31, 2017
Pherotype Polymorphism in Streptococcus pneumoniae Has No Obvious Effects on Population Structure and Recombination.
Natural transformation in the Gram-positive pathogen Streptococcus pneumoniae occurs when cells become "competent," a state that is induced in response to high extracellular concentrations of a secreted peptide signal called...
The evolution of strategy in bacterial warfare via the regulation of bacteriocins and antibiotics.
Bacteria inhibit and kill one another with a diverse array of compounds, including bacteriocins and antibiotics. These attacks are highly regulated, but we lack a clear understanding of the evolutionary logic underlying this...
Purification and characterisation of a quorum quenching AHL-lactonase from the endophytic bacterium Enterobacter sp. CS66.
Rajesh Padumane Shastry, Stephen K Dolan, Yassmin Abdelhamid, Ravishankar Rai Vittal, Martin Welch
May 17, 2018
Orthogonal intercellular signaling for programmed spatial behavior.
Paul K Grant, Neil Dalchau, James R Brown, Fernan Federici, Timothy J Rudge, Boyan Yordanov, Om Patange, Andrew Phillips, Jim Haseloff
Nov 13, 2017
Differential signal sensitivities can contribute to the stability of multispecies bacterial communities.
BACKGROUND: Bacterial species present in multispecies microbial communities often react to the same chemical signal but at vastly different concentrations. The existence of different response thresholds with respect to the same...
Design and synthesis of a biotinylated chemical probe for detecting the molecular targets of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin.
Pseudomonas aeruginosa is a human pathogen associated with a variety of life-threatening nosocomial infections. This organism produces a range of virulence factors which actively cause damage to host tissues. One such virulence...
Environmental potassium regulates bacterial flotation, antibiotic production and turgor pressure in Serratia through the TrkH transporter.
Virulence Regulation and Innate Host Response in the Pathogenicity of Vibrio cholerae.
Thandavarayan Ramamurthy, Ranjan K Nandy, Asish K Mukhopadhyay, Shanta Dutta, Ankur Mutreja, Keinosuke Okamoto, Shin-Ichi Miyoshi, G Balakrish Nair, Amit Ghosh
Oct 14, 2020
The human pathogen Vibrio cholerae is the causative agent of severe diarrheal disease known as cholera. Of the more than 200 "O" serogroups of this pathogen, O1 and O139 cause cholera outbreaks and epidemics. The rest of the...
Mechanism of Signal Transduction By The Staphylococcus Aureus Quorum Sensing Receptor AGRC
Elizabeth A. George Cisar
Jan 01, 0001
Bacteria use receptor histidine kinases to sense extracellular cues and convert them into intracellular signaling events that allow them to respond to their environment. In Staphylococcus aureus, each individual cell must sense...
Histidine Kinase ligand-induced signal transduction AgrC Quorum Sensing Staphylococcus aureus Life Sciences
Published by: Rockefeller University
The evolution of strategy in bacterial warfare via the regulation of bacteriocins and antibiotics
Bacteria inhibit and kill one another with a diverse array of compounds, including bacteriocins and antibiotics. These attacks are highly regulated, but we lack a clear understanding of the evolutionary logic underlying this...
An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei.
The sleeping sickness parasite, Trypanosoma brucei, uses quorum sensing (QS) to balance proliferation and transmission potential in the mammal bloodstream. A signal transduction cascade regulates this process, a component of...
DYRK Trypanosoma DIFFERENTIATION Gene Expression infectious disease microbiology None PARASITE Protein Kinase Amino Acid Motifs Cell Differentiation Gene Expression Regulation Developmental Protein Serine-Threonine Kinases Protein-Tyrosine Kinases Quorum Sensing Signal Transduction Transcription Genetic Trypanosoma brucei brucei
Current Knowledge and Future Directions in Developing Strategies to Combat Pseudomonas aeruginosa Infection.
Stephen K Dolan
Jul 30, 2020
Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.
Lindsay McDonald, Mathieu Cayla, Alasdair Ivens, Binny M Mony, Paula MacGregor, Eleanor Silvester, Kirsty McWilliam, Keith R Matthews
Feb 28, 2019
Trypanosoma brucei, the agents of African trypanosomiasis, undergo density-dependent differentiation in the mammalian bloodstream to prepare for transmission by tsetse flies. This involves the generation of cell-cycle arrested...