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Mouse Papillomavirus L1 and L2 Are Dispensable for Viral Infection and Persistence at Both Cutaneous and Mucosal Tissues
Sarah Brendle, Jingwei J. Li, Nancy M. Cladel, Debra A. Shearer, Lynn R. Budgeon, Karla K. Balogh, Hannah Atkins, Marina Costa-Fujishima, Paul Lopez, Neil D. Christensen, John Doorbar, Thomas T. Murooka, Jiafen Hu
Sep 15, 2021
Papillomavirus L1 and L2, the major and minor capsid proteins, play significant roles in viral assembly, entry, and propagation. In the current study, we investigate the impact of L1 and L2 on viral life cycle and tumor growth...
Mouse Papillomavirus L1 and L2 Are Dispensable for Viral Infection and Persistence at Both Cutaneous and Mucosal Tissues.
Sarah Brendle, Jingwei J Li, Nancy M Cladel, Debra A Shearer, Lynn R Budgeon, Karla K Balogh, Hannah Atkins, Marina Costa-Fujishima, Paul Lopez, Neil D Christensen, John Doorbar, Thomas T Murooka, Jiafen Hu
Oct 29, 2021
Papillomavirus L1 and L2, the major and minor capsid proteins, play significant roles in viral assembly, entry, and propagation. In the current study, we investigate the impact of L1 and L2 on viral life cycle and tumor growth...
IHC ISH L1 mutant L2 mutant RCA RNAscope TEM mouse papillomavirus qPCR tumor growth viral copy number viral production Animals Capsid Proteins Cell Transformation Viral DNA Viral Female Genome Viral Mice Mice Nude Mucous Membrane Mutation Oncogene Proteins Viral Papillomaviridae Skin Virus Replication