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Results: 64
A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention
Natalia del Campo, Tim D Fryer, Young T Hong, Rob Smith, Laurent Brichard, Julio Acosta-Cabronero, Samuel R Chamberlain, Roger Tait, David Izquierdo, Ralf Regenthal, Jonathan Dowson, John Suckling, Jean-Claude Baron, Franklin I Aigbirhio, Trevor W Robbins, Barbara J Sahakian, Ulrich Müller
Aug 19, 2020
Through the combined use of (18)F-fallypride positron emission tomography and magnetic resonance imaging this study examined the neural mechanisms underlying the attentional deficits associated with attention...
18F-fallypride PET Attention deficit/hyperactivity disorder Dopamine methylphenidate sustained attention Adult Attention Deficit Disorder with Hyperactivity Benzamides Corpus Striatum Cross-Over Studies Dopamine Uptake Inhibitors Double-Blind Method Fluorodeoxyglucose F18 Humans Magnetic Resonance Imaging Male Mesencephalon methylphenidate Multimodal Imaging Positron-Emission Tomography Psychiatric Status Rating Scales Radiopharmaceuticals Young Adult
Published by: Brain
Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity.
Liam R Wilson, Deniz Vatansever, Tiina Annus, Guy B Williams, Young T Hong, Tim D Fryer, Peter J Nestor, Anthony J Holland, Shahid H Zaman
Jul 10, 2019
Down's syndrome is a chromosomal disorder that invariably results in both intellectual disability and Alzheimer's disease neuropathology. However, only a limited number of studies to date have investigated intrinsic brain...
Alzheimer's Disease Down's syndrome anti-correlation Default mode network functional connectivity Memory Adult Alzheimer Disease Amyloid Aniline Compounds Carbon Radioisotopes Cerebral Cortex Connectome Cross-Sectional Studies Down Syndrome Female Humans Magnetic Resonance Imaging Male Middle Aged Positron-Emission Tomography Radiopharmaceuticals Thiazoles
Clinical application of autologous technetium-99m-labelled eosinophils to detect focal eosinophilic inflammation in the lung.
Chrystalla Loutsios, Neda Farahi, Rosalind Simmonds, Ian Cullum, Daniel Gillett, Chandra Solanki, Kishor Solanki, John Buscombe, Alison M Condliffe, A Mike Peters, Edwin R Chilvers
Nov 19, 2015
An unusual finding in a 57-year-old woman with new onset hypertension and a diastolic murmur.
CLINICAL INTRODUCTION: A 57-year-old woman presented to our clinic with breathlessness brought on while walking uphill. She had been recently diagnosed with systemic hypertension. There was no known family history of cardiac...
Computed Tomography Angiography Coronary Aneurysm Coronary Angiography Echocardiography Female Fluorodeoxyglucose F18 Heart Murmurs Hemodynamics Humans Hypertension Magnetic Resonance Imaging Middle Aged Multimodal Imaging Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Takayasu arteritis
High Structural Stress and Presence of Intraluminal Thrombus Predict Abdominal Aortic Aneurysm 18F-FDG Uptake
Yuan Huang, Zhongzhao Teng, Maysoon Elkhawad, Jason M Tarkin, Nikhil Joshi, Jonathan R Boyle, John R Buscombe, Timothy D Fryer, Yongxue Zhang, Ah Yeon Park, Ian B Wilkinson, David E Newby, Jonathan H Gillard, James HF Rudd
Nov 10, 2016
abdominal aortic aneurysm Fluorodeoxyglucose F18 Inflammation mechanical stress Positron-Emission Tomography Thrombosis Aged Aged 80 and over Aorta Abdominal Aortic Aneurysm Abdominal Aortic Rupture Aortitis Aortography Biomechanical Phenomena Computed Tomography Angiography Female Finite element analysis Fluorodeoxyglucose F18 Humans Linear Models Male Middle Aged Multivariate Analysis Positron Emission Tomography Computed Tomography Predictive Value of Tests Prognosis Pulsatile Flow Radiographic Image Interpretation Computer-Assisted Radiopharmaceuticals Regional Blood Flow Risk Factors Stress Mechanical Thrombosis Vascular Calcification
Thresholds for Arterial Wall Inflammation Quantified by 18F-FDG PET Imaging
Fleur M van der Valk, Simone L Verweij, Koos AH Zwinderman, Aart C Strang, Yannick Kaiser, Henk A Marquering, Aart J Nederveen, Erik SG Stroes, Hein J Verberne, James HF Rudd
May 05, 2016
(18)F-FDG PET/CT Atherosclerosis Imaging Inflammation thresholds Aged Aorta Aortitis Arteritis Carotid Arteries Carotid Artery Diseases Case-Control Studies Female Fluorodeoxyglucose F18 Humans Male Middle Aged Observer Variation Plaque Atherosclerotic Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Reproducibility of Results
Imaging tumour hypoxia with positron emission tomography.
IN Fleming, R Manavaki, PJ Blower, C West, KJ Williams, AL Harris, J Domarkas, S Lord, C Baldry, FJ Gilbert
Jan 12, 2015
Quantification of Lung PET Images
Protocol for a MULTI-centre feasibility study to assess the use of 99mTc-sestaMIBI SPECT/CT in the diagnosis of kidney tumours (MULTI-MIBI study).
Hannah Warren, Thomas Wagner, Michael A Gorin, Steven Rowe, Beverley Fiona Holman, Deborah Pencharz, Soha El-Sheikh, Ravi Barod, Prasad Patki, Faiz Mumtaz, Axel Bex, Veeru Kasivisvanathan, Caroline M Moore, Nicholas Campain, Jon Cartledge, Andrew Scarsbrook, Fahim Hassan, Tim S O'Brien, Grant D Stewart, Iosif Mendichovszky, Sabina Dizdarevic, Ammar Alanbuki, William H Wildgoose, Tze Wah, Cecilia Vindrola-Padros, Elena Pizzo, Hakim-Moulay Dehbi, Paula Lorgelly, Kurinchi Gurusamy, Mark Emberton, Maxine GB Tran
Feb 24, 2023
INTRODUCTION: The incidence of renal tumours is increasing and anatomic imaging cannot reliably distinguish benign tumours from renal cell carcinoma. Up to 30% of renal tumours are benign, with oncocytomas the most common type....
The pattern of amyloid accumulation in the brains of adults with Down syndrome.
Tiina Annus, Liam R Wilson, Young T Hong, Julio Acosta-Cabronero, Tim D Fryer, Arturo Cardenas-Blanco, Robert Smith, Istvan Boros, Jonathan P Coles, Franklin I Aigbirhio, David K Menon, Shahid H Zaman, Peter J Nestor, Anthony J Holland
Aug 18, 2015
Standardized Index of Shape (DCE-MRI) and Standardized Uptake Value (PET/CT)
Antonella Petrillo, Roberta Fusco, Mario Petrillo, Vincenza Granata, Paolo Delrio, Francesco Bianco, Biagio Pecori, Gerardo Botti, Fabiana Tatangelo, Corradina Caracò, Luigi Aloj, Antonio Avallone, Secondo Lastoria
May 03, 2019
PURPOSE: To investigate dynamic contrast enhanced-MRI (DCE-MRI) in the preoperative chemo-radiotherapy (CRT) assessment for locally advanced rectal cancer (LARC) compared to18F-fluorodeoxyglucose positron emission...
DCE-MRI and FDG-PET/CT neoadjuvant chemo-radiotherapy rectal cancer treatment response assessment Adult Aged Area Under Curve Chemoradiotherapy Adjuvant Contrast Media Digestive System Surgical Procedures Female Fluorodeoxyglucose F18 Humans Magnetic Resonance Imaging Magnetite Nanoparticles Male Middle Aged Neoadjuvant Therapy Perfusion Imaging Positron Emission Tomography Computed Tomography Predictive Value of Tests ROC Curve Radiopharmaceuticals Rectal Neoplasms Regional Blood Flow Remission Induction Reproducibility of Results Siloxanes Treatment Outcome
Novel Approach to Imaging Active Takayasu Arteritis Using Somatostatin Receptor Positron Emission Tomography/Magnetic Resonance Imaging.
Jason M Tarkin, Christopher Wall, Deepa Gopalan, Luigi Aloj, Roido Manavaki, Tim D Fryer, Eric O Aboagye, Martin R Bennett, James E Peters, James HF Rudd, Justin C Mason
Jan 08, 2020
Takayasu arteritis Aortic Diseases Molecular Imaging positron emission tomography Vasculitis Adult Aorta Biomarkers Female Fluorodeoxyglucose F18 Glucocorticoids Humans Immunosuppressive Agents Magnetic Resonance Imaging Middle Aged Molecular Imaging Organometallic Compounds Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Receptors Somatostatin Takotsubo cardiomyopathy Treatment Outcome
Magnetic Resonance Imaging Is More Sensitive Than PET for Detecting Treatment-Induced Cell Death-Dependent Changes in Glycolysis.
Richard L Hesketh, Jiazheng Wang, Alan J Wright, David Y Lewis, Alice E Denton, Richard Grenfell, Jodi L Miller, Robert Bielik, Marcel Gehrung, Maria Fala, Susana Ros, Bangwen Xie, De-En Hu, Kevin M Brindle
May 17, 2019
Metabolic imaging has been widely used to measure the early responses of tumors to treatment. Here, we assess the abilities of PET measurement of [18F]FDG uptake and MRI measurement of hyperpolarized [1-13C]pyruvate metabolism...
Adenocarcinoma Animals Antineoplastic Agents Carbon Isotopes Cell Death Cell Line Tumor Colorectal Neoplasms Female Fluorodeoxyglucose F18 Glycolysis Heterografts Humans Lactic Acid Magnetic Resonance Imaging Mice Inbred BALB C Mice Nude Positron-Emission Tomography Pyruvic Acid Radiopharmaceuticals Receptors TNF-Related Apoptosis-Inducing Ligand Triple Negative Breast Neoplasms
68Ga-DOTATATE PET Identifies Residual Myocardial Inflammation and Bone Marrow Activation After Myocardial Infarction.
Jason M Tarkin, Claudia Calcagno, Marc R Dweck, Nicholas R Evans, Mohammed M Chowdhury, Deepa Gopalan, David E Newby, Zahi A Fayad, Martin R Bennett, James HF Rudd
Mar 04, 2019
Myocardial infarction (MI) healing occurs in two phases: first an inflammatory phase, where clearance of necrotic debris occurs, followed by a reparative phase characterized by angiogenesis, granulation tissue formation and...
The emerging role of cell surface receptor and protein binding radiopharmaceuticals in cancer diagnostics and therapy.
Luigi Aloj, Bala Attili, Doreen Lau, Corradina Caraco, Laura M Lechermann, Iosif A Mendichovszky, Ines Harper, Heok Cheow, Ruth T Casey, Evis Sala, Fiona J Gilbert, Ferdia A Gallagher
Jun 15, 2020
Severity of Psoriasis Associates With Aortic Vascular Inflammation Detected by FDG PET/CT and Neutrophil Activation in a Prospective Observational Study.
Haley B Naik, Balaji Natarajan, Elena Stansky, Mark A Ahlman, Heather Teague, Taufiq Salahuddin, Qimin Ng, Aditya A Joshi, Parasuram Krishnamoorthy, Jenny Dave, Shawn M Rose, Julia Doveikis, Martin P Playford, Ronald B Prussick, Alison Ehrlich, Mariana J Kaplan, Benjamin N Lockshin, Joel M Gelfand, Nehal N Mehta
Nov 04, 2015
CT PET Inflammation Neutrophils psoriasis vascular inflammation Adult Aortitis Biomarkers Case-Control Studies Female Fluorodeoxyglucose F18 Humans Immunity Innate Inflammation Mediators Leukocyte Count Male Middle Aged Multimodal Imaging Neutrophil Activation Neutrophils Positron-Emission Tomography Predictive Value of Tests Prospective Studies Psoriasis Radiopharmaceuticals Severity of Illness Index Tomography X-Ray Computed
Advances in PET to assess pulmonary inflammation
Laurence Vass, Marie Fisk, Sarah Lee, Frederick J Wilson, Joseph Cheriyan, Ian Wilkinson
Jul 16, 2020
Atherosclerosis imaging using PET
Rouchelle S Sriranjan, Jason M Tarkin, Nicholas R Evans, Elizabeth PV Le, Mohammed M Chowdhury, James HF Rudd
Sep 19, 2019
PET imaging is able to harness biological processes to characterise high-risk features of atherosclerotic plaque prone to rupture. Current radiotracers are able to track inflammation, microcalcification, hypoxia, and...
Rapid Imaging of Tumor Cell Death in vivo using the C2A domain of Synaptotagmin-I
AA Neves, B Xie, S Fawcett, IS Alam, TH Witney, MM de Backer, J Summers, W Hughes, S McGuire, D Soloviev, J Miller, WJ Howat, D-E Hu, TB Rodrigues, DY Lewis, KM Brindle
Mar 31, 2017
Para-chloro-2-[18F]fluoroethyl-etomidate
Isabella Silins, Anders Sundin, Patrik Nordeman, Mahabuba Jahan, Sergio Estrada, Azita Monazzam, Mark Lubberink, Franklin Aigbirhio, Per Hellman, Gunnar Antoni
May 21, 2021
Introduction: [11C]Metomidate ([11C]MTO), the methyl ester analogue of etomidate, was developed as a positron emission tomography (PET) radiotracer for adrenocortical tumours and has also been suggested for imaging in primary...
18F-CETO Adrenal masses Adrenal tracer positron emission tomography primary aldosteronism Adrenal Cortex Adrenal Cortex Neoplasms Animals Drug Evaluation Preclinical Etomidate Fluorine Radioisotopes Humans hyperaldosteronism Macaca fascicularis Mice Positron-Emission Tomography Radiopharmaceuticals Rats Tissue Distribution
Pattern of arterial inflammation and inflammatory markers in people living with HIV compared with uninfected people.
Nevio Taglieri, Rachele Bonfiglioli, Isabella Bon, Pietro Malosso, Andrej Corovic, Matteo Bruno, Elizabeth Le, Bianca Granozzi, Tullio Palmerini, Gabriele Ghetti, Martina Tamburello, Antonio Giulio Bruno, Francesco Saia, Jason M Tarkin, James HF Rudd, Leonardo Calza, Stefano Fanti, Maria Carla Re, Nazzareno Galié
Aug 03, 2022
18F-fluorodeoxyglucose-positron emission tomography Arterial inflammation HIV Arteritis Atherosclerosis Biomarkers Fluorodeoxyglucose F18 HIV Infections Humans Inflammation Positron Emission Tomography Computed Tomography Radiopharmaceuticals Tomography X-Ray Computed Vascular Cell Adhesion Molecule-1
Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation.
Yohana C Toner, Adam A Ghotbi, Sonum Naidu, Ken Sakurai, Mandy MT van Leent, Stefan Jordan, Farideh Ordikhani, Letizia Amadori, Alexandros Marios Sofias, Elizabeth L Fisher, Alexander Maier, Nathaniel Sullivan, Jazz Munitz, Max L Senders, Christian Mason, Thomas Reiner, Georgios Soultanidis, Jason M Tarkin, James HF Rudd, Chiara Giannarelli, Jordi Ochando, Carlos Pérez-Medina, Andreas Kjaer, Willem JM Mulder, Zahi A Fayad, Claudia Calcagno
May 15, 2022
An Automated Method for Artifical Intelligence Assisted Diagnosis of Active Aortitis Using Radiomic Analysis of FDG PET-CT Images.
Lisa M Duff, Andrew F Scarsbrook, Nishant Ravikumar, Russell Frood, Gijs D van Praagh, Sarah L Mackie, Marc A Bailey, Jason M Tarkin, Justin C Mason, Kornelis SM van der Geest, Riemer HJA Slart, Ann W Morgan, Charalampos Tsoumpas
Mar 06, 2023
Synergistic application of pulmonary 18F-FDG PET/HRCT and computer-based CT analysis with conventional severity measures to refine current risk stratification in idiopathic pulmonary fibrosis (IPF).
Francesco Fraioli, Maria Lyasheva, Joanna C Porter, Jamshed Bomanji, Robert I Shortman, Raymond Endozo, Simon Wan, Linda Bertoletti, Maria Machado, Balaji Ganeshan, Thida Win, Ashley M Groves
Jul 07, 2020
INTRODUCTION: To investigate the combined performance of quantitative CT (qCT) following a computer algorithm analysis (IMBIO) and 18F-FDG PET/CT to assess survival in patients with idiopathic pulmonary fibrosis (IPF). METHODS...
Fluorine-18 FDG and pulmonary vessels Idiopathic Pulmonary Fibrosis positron emission tomography Quantitative computer analysis Aged Aged 80 and over Female Fluorodeoxyglucose F18 Humans Image Processing Computer-Assisted Male Middle Aged Positron Emission Tomography Computed Tomography Predictive Value of Tests pulmonary fibrosis Radiopharmaceuticals Survival Analysis
Repeatability of quantitative FDG-PET/CT and contrast-enhanced CT in recurrent ovarian carcinoma
Andrea G Rockall, Norbert Avril, Raymond Lam, Robert Iannone, P David Mozley, Christine Parkinson, Donald Bergstrom, Evis Sala, Shah-Jalal Sarker, Iain A McNeish, James D Brenton
Jul 14, 2014
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