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Results: 6
Multicentric breast cancer with heterogeneous histopathology
Giovanni Corso, Francesca Magnoni, Elena Provenzano, Antonia Girardi, Monica Iorfida, Alessandra Margherita De Scalzi, Alessandra Invento, Marco Colleoni, Enrico Cassano, Chiara Trentin, Roberto Lo Gullo, Gabriella Pravettoni, Laura Gilardi, Chiara Maria Grana, Mattia Intra, Viviana Galimberti, Paolo Veronesi, Francesca De Lorenzi, Maria Cristina Leonardi
Feb 26, 2020
Multiple synchronous (multifocal or multicentric) ipsilateral breast cancers with heterogeneous histopathology are a rare clinical occurrence, however, their incidence is increasing due to the use of MRI for breast cancer...
Breast Cancer breast cancer histotypes Diagnosis lobular carcinoma multicentric cancer Multidisciplinary team multifocal cancer Prognosis surgical management Breast Neoplasms Combined Modality Therapy Disease Management Disease Susceptibility Female Genetic Predisposition to Disease Humans Lymphoscintigraphy Multimodal Imaging Neoplasm Grading Neoplasm Staging Prognosis Retreatment Sentinel Lymph Node Biopsy Treatment Outcome Tumor Burden
Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase
Claire M Connell, Rebecca Brais, Hayley Whitaker, Sara Upponi, Ian Beh, Jane Risdall, Pippa Corrie, Tobias Janowitz, Duncan I Jodrell
Jan 09, 2020
Cytidine Deaminase DRUG METABOLISM Gemcitabine Pancreatic Adenosquamous Carcinoma Antimetabolites Antineoplastic Carcinoma Adenosquamous Chemotherapy Adjuvant Cytidine Deaminase Deoxycytidine Female Gene Expression Humans Immunohistochemistry Magnetic Resonance Imaging Middle Aged Pancreatic Neoplasms Recurrence Retreatment Tomography X-Ray Computed Treatment Outcome Gemcitabine
Progression and treatment rates using an active surveillance protocol incorporating image-guided baseline biopsies and multiparametric magnetic resonance imaging monitoring for men with favourable-risk prostate cancer.
David Thurtle, Tristan Barrett, Vineetha Thankappan-Nair, Brendan Koo, Anne Warren, Christof Kastner, Kasra Saeb-Parsy, Jenna Kimberley-Duffell, Vincent J Gnanapragasam
Apr 26, 2018
OBJECTIVE: To assess early outcomes since the introduction of an active surveillance (AS) protocol incorporating multiparametric magnetic resonance imaging (mpMRI)-guided baseline biopsies and image-based surveillance. PATIENTS...
#PCSM #ProstateCancer active surveillance localized prostate cancer low-risk prostate cancer mpMRI Aged Aged 80 and over Disease Progression Humans Image-guided biopsy Magnetic Resonance Imaging Interventional Male Middle Aged Prospective Studies Prostate Prostate-specific antigen Prostatic Neoplasms Retreatment Treatment Outcome Watchful Waiting
POSEIDON Trial Phase 1b Results
Richard D Baird, Annelot GJ van Rossum, Mafalda Oliveira, Karin Beelen, Meiling Gao, Mariette Schrier, Ingrid AM Mandjes, Javier Garcia-Corbacho, Anne-Laure Vallier, Greig Dougall, Erik Van Werkhoven, Constanza Linossi, Sanjeev Kumar, Harm van Tinteren, Maurizio Callari, Emma Beddowes, José-Manuel Perez-Garcia, Hilde Rosing, Else Platte, Petra Nederlof, Margaret Schot, Aurelia de Vries Schultink, René Bernards, Cristina Saura, William Gallagher, Javier Cortès, Carlos Caldas, Sabine C Linn
Oct 02, 2019
PURPOSE: The strategy of combining endocrine therapy with PI3K-mTOR inhibition has shown promise in estrogen receptor (ER)-positive breast cancer, but new agents and combinations with a better therapeutic index are urgently...
Adult Aged Aged 80 and over Antineoplastic Combined Chemotherapy Protocols Biomarkers Tumor Breast Neoplasms Circulating Tumor DNA Female Humans Imidazoles Middle Aged Mutation Neoplasm Metastasis Neoplasm Staging Oxazepines Receptors Estrogen Receptors Progesterone Retreatment Tamoxifen Treatment Outcome
What are the important morbidities associated with paediatric cardiac surgery? A mixed methods study.
Katherine L Brown, Christina Pagel, Deborah Ridout, Jo Wray, David Anderson, David J Barron, Jane Cassidy, Peter Davis, Emma Hudson, Alison Jones, Andrew McLean, Stephen Morris, Warren Rodrigues, Karen Sheehan, Serban Stoica, Shane M Tibby, Thomas Witter, Victor T Tsang, Cardiac Impact Study Group
Sep 11, 2020
OBJECTIVES: Given the current excellent early mortality rates for paediatric cardiac surgery, stakeholders believe that this important safety outcome should be supplemented by a wider range of measures. Our objectives were to...
cardiac surgery complications Morbidity outcome Paediatrics Quality of life Adolescent Age Factors Cardiac Surgical Procedures Child Child Preschool Female Heart Diseases Humans Incidence Infant Infant Newborn Logistic Models Male Medical Audit multimorbidity Postoperative Complications Prospective Studies Quality Indicators Health Care Retreatment Risk Assessment Risk Factors Time Factors Treatment Outcome United Kingdom
Diagnostic evaluation of magnetization transfer and diffusion kurtosis imaging for prostate cancer detection in a re-biopsy population.
Tristan Barrett, Mary McLean, Andrew N Priest, Edward M Lawrence, Andrew J Patterson, Brendan C Koo, Ilse Patterson, Anne Y Warren, Andrew Doble, Vincent J Gnanapragasam, Christof Kastner, Ferdia A Gallagher
Jun 04, 2018
OBJECTIVE: To evaluate diffusion kurtosis imaging (DKI) and magnetisation transfer imaging (MTI) compared to standard MRI for prostate cancer assessment in a re-biopsy population. METHODS: Thirty-patients were imaged at 3 T...
Diffusion kurtosis imaging Diffusion-weighted imaging MRI Magnetisation transfer imaging Prostate Aged Diffusion Magnetic Resonance Imaging Diffusion tensor imaging Humans Image Interpretation Computer-Assisted Image-guided biopsy Magnetic Resonance Imaging Male Middle Aged Prospective Studies Prostatic Neoplasms ROC Curve Retreatment