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PET-guided repeat transsphenoidal surgery for previously deemed unresectable lateral disease in acromegaly.
Waiel A Bashari, Russell Senanayake, Olympia Koulouri, Daniel Gillett, James MacFarlane, Andrew S Powlson, Antia Fernandez-Pombo, Gul Bano, Andrew J Martin, Daniel Scoffings, Heok Cheow, Iosif Mendichovszky, James Tysome, Neil Donnelly, Thomas Santarius, Angelos Kolias, Richard Mannion, Mark Gurnell
Jun 23, 2020
DA = dopamine agonist FSPGR = fast spoiled gradient-recalled echo GH = growth hormone IGF-1 = insulin-like growth factor 1 MDT = multidisciplinary team Met-PET = PET using 11C-methionine Met-PET/MRCR Met-PET/MRCR = Met-PET coregistered with volumetric MRI PA = pituitary adenoma RT = radiotherapy SSA = somatostatin analog TSS = transsphenoidal surgery ULN = upper limit of normal acromegaly extended TSS lateral parasellar acromegaly Adult Aged Female Humans Male Middle Aged Positron Emission Tomography Computed Tomography Proof of Concept Study Reoperation Sphenoid Bone