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Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6.
Yongxu Lu, Jennifer H Stuart, Callum Talbot-Cooper, Shuchi Agrawal-Singh, Brian Huntly, Andrei I Smid, Joseph S Snowden, Liane Dupont, Geoffrey L Smith
May 10, 2019
STAT2 recruitment histone deactylase 4 Immune Evasion type I interferon signaling vaccinia virus protein C6 Cell Line Cell Line Tumor DNA Viruses HEK293 Cells HeLa Cells Herpesvirus 1 Human Histone Deacetylases Humans Interferon Type I Repressor Proteins Signal Transduction Vaccinia vaccinia virus Viral Proteins Virus Replication