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Pros and cons of different therapeutic antibody formats for recombinant antivenom development.
Andreas H Laustsen, José María Gutiérrez, Cecilie Knudsen, Kristoffer H Johansen, Erick Bermúdez-Méndez, Felipe A Cerni, Jonas A Jürgensen, Line Ledsgaard, Andrea Martos-Esteban, Mia Øhlenschlæger, Urska Pus, Mikael R Andersen, Bruno Lomonte, Mikael Engmark, Manuela B Pucca
Jun 19, 2018
Antibody technologies are being increasingly applied in the field of toxinology. Fuelled by the many advances in immunology, synthetic biology, and antibody research, different approaches and antibody formats are being...
Adverse reactions Animal envenoming Antibodies Antibody expression Antivenom Antivenom design Biotechnology Immunogenicity Neglected tropical diseases pharmacodynamics Pharmacokinetics Recombinant antivenom Scorpion sting Snakebite Spider bite Venom Venom neutralization Animals Antibodies Antivenins Camelus Humans Recombinant Proteins Venoms