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BACKGROUND: Protein transporters translocate hydrophilic segments of polypeptide across hydrophobic cell membranes. Two protein transporters are ubiquitous and date back to the last universal common ancestor: SecY and YidC. SecY...

Membrane protein integration Oxa1 superfamily Protein translocation Protocell evolution SecY YidC Bacterial Proteins Cell Membrane Escherichia coli Proteins Hydrophobic and Hydrophilic Interactions Membrane Proteins Membrane Transport Proteins

BACKGROUND: Protein transporters translocate hydrophilic segments of polypeptide across hydrophobic cell membranes. Two protein transporters are ubiquitous and date back to the last universal common ancestor: SecY and YidC. SecY...

RESEARCH ARTICLE Oxa1 superfamily Protein translocation Membrane protein integration Protocell evolution SecY YidC