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Targeting senescent cells in translational medicine.
Organismal ageing is a complex process driving progressive impairment of functionality and regenerative potential of tissues. Cellular senescence is a state of stable cell cycle arrest occurring in response to damage and stress...
Cellular senescence in cancer
Hui-Ling Ou, Reuben Hoffmann, Cristina González-López, Gary J Doherty, James E Korkola, Daniel Muñoz-Espín
Jan 18, 2021
Senescence refers to a cellular state featuring a stable cell-cycle arrest triggered in response to stress. This response also involves other distinct morphological and intracellular changes including alterations in gene...
Cellular senescence in cancer
Hui‐Ling Ou, Reuben Hoffmann, Cristina González‐López, Gary J. Doherty, James E. Korkola, Daniel Muñoz‐Espín
Oct 01, 2021
Senescence refers to a cellular state featuring a stable cell‐cycle arrest triggered in response to stress. This response also involves other distinct morphological and intracellular changes including alterations in gene...
Published by: Molecular Oncology