Search
Results: 1
Agarose microgel culture delineates lumenogenesis in naive and primed human pluripotent stem cells.
Magdalena Schindler, Dylan Siriwardena, Timo N Kohler, Anna L Ellermann, Erin Slatery, Clara Munger, Florian Hollfelder, Thorsten E Boroviak
May 03, 2021
Human periimplantation development requires the transformation of the naive pluripotent epiblast into a polarized epithelium. Lumenogenesis plays a critical role in this process, as the epiblast undergoes rosette formation and...
Epiblast epiblast spheroid human development lumenogenesis microfluidic platform microgel suspension culture naive pluripotency primed pluripotency Self-organization Cell Culture Techniques Cell Differentiation Cell Lineage Cell Survival Cells Immobilized Germ Layers Humans Induced Pluripotent Stem Cells Microgels Morphogenesis Protein Kinase Inhibitors Sepharose Spheroids Cellular rho-Associated Kinases