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Decreased Water Mobility Contributes To Increased α‐Synuclein Aggregation**
Amberley D Stephens, Johanna Kölbel, Rani Moons, Chyi Wei Chung, Michael T Ruggiero, Najet Mahmoudi, Talia A Shmool, Thomas M McCoy, Daniel Nietlispach, Alexander F Routh, Frank Sobott, J Axel Zeitler, Gabriele S Kaminski Schierle
Jan 12, 2023
The solvation shell is essential for the folding and function of proteins, but how it contributes to protein misfolding and aggregation has still to be elucidated. We show that the mobility of solvation shell H2O molecules...
Decreased Water Mobility Contributes To Increased α-Synuclein Aggregation.
Amberley D Stephens, Johanna Kölbel, Rani Moons, Chyi Wei Chung, Michael T Ruggiero, Najet Mahmoudi, Talia A Shmool, Thomas M McCoy, Daniel Nietlispach, Alexander F Routh, Frank Sobott, J Axel Zeitler, Gabriele S Kaminski Schierle
Jan 12, 2023
The solvation shell is essential for the folding and function of proteins, but how it contributes to protein misfolding and aggregation has still to be elucidated. We show that the mobility of solvation shell H2 O molecules...