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Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases
Claire Cury, Stanley Durrleman, David M Cash, Marco Lorenzi, Jennifer M Nicholas, Martina Bocchetta, John C van Swieten, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B Frisoni, Robert Laforce, Elizabeth Finger, Alexandre de Mendonça, Sandro Sorbi, Sebastien Ourselin, Jonathan D Rohrer, Marc Modat, GENFI Genetic FTD Initiative
Jan 02, 2019
Brain atrophy as measured from structural MR images, is one of the primary imaging biomarkers used to track neurodegenerative disease progression. In diseases such as frontotemporal dementia or Alzheimer's disease, atrophy can...