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Molecular characterization of Glaesserella parasuis strains isolated from North America, Europe and Asia by serotyping PCR and LS-PCR.
Nubia Macedo, Marcelo Gottschalk, Katrin Strutzberg-Minder, Chao Nguyen Van, Lijun Zhang, Geng Zou, Rui Zhou, Thaire Marostica, Maria Jose Clavijo, Alexander Tucker, Virginia Aragon
Jun 13, 2021
Glaesserella parasuis strains were characterized by serotyping PCR, vtaA virulence marker Leader Sequence (LS)-PCR, clinical significance, and geographic region. Overall, the serovars 4, 5/12, 7, 1, and 13 were the most commonly...
High turnover drives prolonged persistence of influenza in managed pig herds.
Virginia E Pitzer, Ricardo Aguas, Steven Riley, Willie LA Loeffen, James LN Wood, Bryan T Grenfell
Aug 26, 2016
Evaluation of the recombinant proteins RlpB and VacJ as a vaccine for protection against Glaesserella parasuis in pigs.
Samantha J Hau, Shi-Lu Luan, Crystal L Loving, Tracy L Nicholson, Jinhong Wang, Sarah E Peters, David Seilly, Lucy A Weinert, Paul R Langford, Andrew N Rycroft, Brendan W Wren, Duncan J Maskell, Alexander W Tucker, Susan L Brockmeier, BRaDP1T Consortium
Jun 08, 2020
BACKGROUND: Glaesserella parasuis, the causative agent of Glӓsser's disease, is widespread in swine globally resulting in significant economic losses to the swine industry. Prevention of Glӓsser's disease in pigs has been...
Glaesserella parasuis Glässer’s disease Subunit vaccine Animals Antibodies Bacterial Bacterial Proteins Bacterial Vaccines Haemophilus Infections Haemophilus Vaccines Haemophilus parasuis Recombinant Proteins Serogroup Sus scrofa Swine Swine Diseases Tissue Culture Techniques Vaccination vaccines Subunit
A Survey of Chinese Pig Farms and Human Healthcare Isolates Reveals Separate Human and Animal Methicillin-Resistant Staphylococcus aureus Populations.
Geng Zou, Marta Matuszewska, Ming Jia, Jianwei Zhou, Xiaoliang Ba, Juan Duan, Caishi Zhang, Jian Zhao, Meng Tao, Jingyan Fan, Xiangming Zhang, Wenping Jin, Tianpen Cui, Xianyu Zeng, Min Jia, Xiaojuan Qian, Chao Huang, Wenxiao Zhuo, Zhiming Yao, Lijun Zhang, Shaowen Li, Lu Li, Qi Huang, Bin Wu, Huanchun Chen, Alexander W Tucker, Andrew J Grant, Mark A Holmes, Rui Zhou
Jan 04, 2022
There has been increasing concern that the overuse of antibiotics in livestock farming is contributing to the burden of antimicrobial resistance in people. Farmed animals in Europe and North America, particularly pigs, provide a...
Pathogenesis of Korean SapelovirusA in piglets and chicks.
Deok-Song Kim, Mun-Il Kang, Kyu-Yeol Son, Geon-Yong Bak, Jun-Gyu Park, Myra Hosmillo, Ja-Young Seo, Ji-Yun Kim, Mia Madel Alfajaro, Mahmoud Soliman, Yeong-Bin Baek, Eun-Hyo Cho, Ju-Hwan Lee, Joseph Kwon, Jong-Soon Choi, Ian Goodfellow, Kyoung-Oh Cho
Oct 13, 2016
Kate J Howell, Sarah E Peters, Jinhong Wang, Juan Hernandez-Garcia, Lucy A Weinert, Shi-Lu Luan, Roy R Chaudhuri, Øystein Angen, Virginia Aragon, Susanna M Williamson, Julian Parkhill, Paul R Langford, Andrew N Rycroft, Brendan W Wren, Duncan J Maskell, Alexander W Tucker, BRaDP1T Consortium
Sep 23, 2015
Increased risk of A(H1N1)pdm09 influenza infection in UK pig industry workers compared to a general population cohort.
Ellen Fragaszy, David A Ishola, Ian H Brown, Joanne Enstone, Jonathan S Nguyen-Van-Tam, Robin Simons, Alexander W Tucker, Barbara Wieland, Susanna M Williamson, Andrew C Hayward, Flu Watch Group, James LN Wood, Combating Swine Influenza (COSI) Consortium
Feb 12, 2016
Dynamics of Japanese encephalitis virus transmission among pigs in Northwest Bangladesh and the potential impact of pig vaccination.
Salah Uddin Khan, Henrik Salje, A Hannan, Md Atiqul Islam, AA Mamun Bhuyan, Md Ariful Islam, M Ziaur Rahman, Nazmun Nahar, M Jahangir Hossain, Stephen P Luby, Emily S Gurley
Feb 15, 2021
BACKGROUND: Japanese encephalitis (JE) virus infection can cause severe disease in humans, resulting in death or permanent neurologic deficits among survivors. Studies indicate that the incidence of JE is high in northwestern...
Aetiology and Potential Animal Exposure in Central Nervous System Infections in Vietnam.
Hannah E Brindle, Behzad Nadjm, Marc Choisy, Rob Christley, Michael Griffiths, Stephen Baker, Juliet E Bryant, James I Campbell, Van Vinh Chau Nguyen, Thi Ngoc Diep Nguyen, Ty Thi Hang Vu, Van Hung Nguyen, Bao Long Hoang, Xuan Luat Le, Ha My Pham, Thi Dieu Ngan Ta, Dang Trung Nghia Ho, Thua Nguyen Tran, Thi Han Ny Nguyen, My Phuc Tran, Thi Hong Phuong Pham, Van Tan Le, Dac Thuan Nguyen, Thi Thu Trang Hau, Ngoc Vinh Nguyen, Heiman FL Wertheim, Guy E Thwaites, H Rogier van Doorn, VIZIONS consortium
Feb 03, 2023
An estimated 73% of emerging infections are zoonotic in origin, with animal contact and encroachment on their habitats increasing the risk of spill-over events. In Vietnam, close exposure to a wide range of animals and animal...
Pathotyping the Zoonotic Pathogen Streptococcus suis
Thomas M Wileman, Lucy A Weinert, Kate J Howell, Jinhong Wang, Sarah E Peters, Susanna M Williamson, Jerry M Wells, Paul R Langford, Andrew N Rycroft, Brendan W Wren, Duncan J Maskell, Alexander W Tucker
May 03, 2019
Streptococcus suis molecular diagnostics pathotyping SURVEILLANCE virulence markers Animals Carrier State England Genetic Markers Genome Bacterial Molecular Diagnostic Techniques Multiplex Polymerase Chain Reaction Palatine Tonsil Streptococcal Infections Streptococcus suis Swine Swine Diseases Virulence Wales
Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis.
Lucy A Weinert, Roy R Chaudhuri, Jinhong Wang, Sarah E Peters, Jukka Corander, Thibaut Jombart, Abiyad Baig, Kate J Howell, Minna Vehkala, Niko Välimäki, David Harris, Tran Thi Bich Chieu, Nguyen Van Vinh Chau, James Campbell, Constance Schultsz, Julian Parkhill, Stephen D Bentley, Paul R Langford, Andrew N Rycroft, Brendan W Wren, Jeremy Farrar, Stephen Baker, Ngo Thi Hoa, Matthew TG Holden, Alexander W Tucker, Duncan J Maskell, BRaDP1T Consortium
Apr 30, 2015
Rapid host switching in generalist Campylobacter strains erodes the signal for tracing human infections.
Bethany L Dearlove, Alison J Cody, Ben Pascoe, Guillaume Méric, Daniel J Wilson, Samuel K Sheppard
Jul 24, 2015
Factors associated with pleurisy in pigs
HC Jäger, TJ McKinley, JLN Wood, GP Pearce, S Williamson, B Strugnell, S Done, H Habernoll, A Palzer, AW Tucker
Apr 12, 2017
Full genomic characterization of a porcine rotavirus strain detected in an asymptomatic piglet in Accra, Ghana.
Samuel CB Stubbs, Osbourne Quaye, Maame Ekua Acquah, Samuel Mawuli Adadey, Iain RL Kean, Srishti Gupta, Barbara A Blacklaws
Jan 07, 2020
Hepatitis E in southern Vietnam
A Berto, HA Pham, TTN Thao, NHT Vy, SL Caddy, R Hiraide, NT Tue, I Goodfellow, JJ Carrique-Mas, GE Thwaites, S Baker, MF Boni, VIZIONS consortium
Apr 10, 2019
Viral pathogens account for a significant proportion of the burden of emerging infectious diseases in humans. The Wellcome Trust-Vietnamese Initiative on Zoonotic Infections (WT-VIZIONS) is aiming to understand the circulation...
Effects of Environmental and Management-Associated Factors on Prevalence and Diversity of Streptococcus suis in Clinically Healthy Pig Herds in China and the United Kingdom.
Geng Zou, Jianwei Zhou, Ran Xiao, Liangsheng Zhang, Yuting Cheng, Hui Jin, Lu Li, Lijun Zhang, Bin Wu, Ping Qian, Shaowen Li, Lixin Ren, Jinhong Wang, Olusegun Oshota, Juan Hernandez-Garcia, Thomas M Wileman, Stephen Bentley, Lucy Weinert, Duncan J Maskell, AW Dan Tucker, Rui Zhou
Mar 29, 2018
Streptococcus suis, a global zoonosis of pigs, shows regional differences in the prevalence of human-associated disease for Asian and non-Asian countries. The isolation rates and diversities of S. suis on tonsils of healthy...
Streptococcus suis clinically healthy pig herds environmental factors management-associated factors Age Factors Animal Husbandry Animals China genetic variation Genome Bacterial Longitudinal Studies prevalence Streptococcal Infections Streptococcus suis Swine Swine Diseases Temperature United Kingdom
Characterization of co-circulating swine influenza A viruses in North America and the identification of a novel H1 genetic clade with antigenic significance.
Tavis K Anderson, Brian A Campbell, Martha I Nelson, Nicola S Lewis, Alicia Janas-Martindale, Mary Lea Killian, Amy L Vincent
Jun 02, 2015
Antigenic drift EPIDEMIOLOGY Influenza A virus Swine vaccines Zoonotic diseases Animals Cluster Analysis genetic variation Genotype Hemagglutinin Glycoproteins Influenza Virus Influenza A virus molecular epidemiology North America Orthomyxoviridae Infections Phylogeny RNA Viral Sequence Analysis DNA Sequence Homology Swine Swine Diseases
Analysis of Campylobacter jejuni infection in the gnotobiotic piglet and genome-wide identification of bacterial factors required for infection
SPW de Vries, A Linn, K Macleod, A MacCallum, SP Hardy, G Douce, E Watson, MP Dagleish, H Thompson, A Stevenson, D Kennedy, A Baig, C Coward, DJ Maskell, DGE Smith, AJ Grant, P Everest
Aug 17, 2017
"Pathotyping" Multiplex PCR Assay for Haemophilus parasuis
Kate J Howell, Lucy A Weinert, Sarah E Peters, Jinhong Wang, Juan Hernandez-Garcia, Roy R Chaudhuri, Shi-Lu Luan, Øystein Angen, Virginia Aragon, Susanna M Williamson, Paul R Langford, Andrew N Rycroft, Brendan W Wren, Duncan J Maskell, Alexander W Tucker
Aug 22, 2017
Haemophilus parasuis is a diverse bacterial species that is found in the upper respiratory tracts of pigs and can also cause Glässer's disease and pneumonia. A previous pangenome study of H. parasuis identified 48 genes that...
Genetic Diversity of Porcine Circovirus 2 in Wild Boar and Domestic Pigs in Ukraine.
Nataliia Rudova, Jeremy Buttler, Ganna Kovalenko, Mykola Sushko, Vitaliy Bolotin, Larysa Muzykina, Oleksandr Zinenko, Borys Stegniy, Yurii Dunaiev, Mykola Sytiuk, Anton Gerilovych, Devin M Drown, Eric Bortz, Oleksii Solodiankin
Jun 29, 2022
Porcine circovirus type 2 (PCV2) is responsible for a number of porcine circovirus-associated diseases (PCVAD) that can severely impact domestic pig herds. For a non-enveloped virus with a small genome (1.7 kb ssDNA), PCV2 is...
Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014.
Juan Hernandez-Garcia, Jinhong Wang, Olivier Restif, Mark A Holmes, Alison E Mather, Lucy A Weinert, Thomas M Wileman, Jill R Thomson, Paul R Langford, Brendan W Wren, Andrew Rycroft, Duncan J Maskell, Alexander W Tucker, BRaDP1T Consortium
Jun 27, 2017
Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus.
The global antigenic diversity of swine influenza A viruses.
Nicola S Lewis, Colin A Russell, Pinky Langat, Tavis K Anderson, Kathryn Berger, Filip Bielejec, David F Burke, Gytis Dudas, Judith M Fonville, Ron AM Fouchier, Paul Kellam, Bjorn F Koel, Philippe Lemey, Tung Nguyen, Bundit Nuansrichy, Js Malik Peiris, Takehiko Saito, Gaelle Simon, Eugene Skepner, Nobuhiro Takemae, ESNIP3 consortium, Richard J Webby, Kristien Van Reeth, Sharon M Brookes, Lars Larsen, Simon J Watson, Ian H Brown, Amy L Vincent
Apr 08, 2016
Weakly haemolytic variants of Brachyspira hyodysenteriae newly emerged in Europe belong to a distinct subclade with unique genetic properties.
Roderick M Card, Tom La, Eric R Burrough, Richard J Ellis, Javier Nunez-Garcia, Jill R Thomson, Maxime Mahu, Nyree D Phillips, David J Hampson, Judith Rohde, Alexander W Tucker
May 28, 2019
Brachyspira (B.) hyodysenteriae is widespread globally, and can cause mucohaemorrhagic colitis (swine dysentery, SD) with severe economic impact in infected herds. Typical strains of B. hyodysenteriae are strongly haemolytic on...