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Optineurin (OPTN) is a multifunctional protein involved in autophagy and secretion, as well as nuclear factor κB (NF-κB) and IRF3 signalling, and OPTN mutations are associated with several human diseases. Here, we show that, in...

ATG9A BioID functional proteomics IFN LUBAC Linear ubiquitin NF-κB OPTN TBK1 Cell Cycle Proteins Cytokines Glaucoma Open-Angle Humans Membrane Transport Proteins NF-kappa B Protein Transport Signal Transduction Transcription Factor TFIIIA