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Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency.
Matthew T Rätsep, Stephen D Moore, Salema Jafri, Melissa Mitchell, Hugh JM Brady, Ofer Mandelboim, Mark Southwood, Nicholas W Morrell, Francesco Colucci, Mark L Ormiston
Nov 21, 2018
Natural killer (NK) cells are cytotoxic innate lymphoid cells with an established role in the regulation of vascular structure in pregnancy and cancer. Impaired NK cell function has been identified in patients with pulmonary...
Th17 angiopoietin-2 Interleukin-23 natural killer cells pulmonary hypertension Animals Basic-Leucine Zipper Transcription Factors Disease Models Animal Endothelial Cells Humans Hypertension Pulmonary Killer Cells Natural Lung Mice Natural Cytotoxicity Triggering Receptor 1 Pulmonary Artery Vascular Remodeling