Search
Results: 5
Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring
Jan Uter, Marcus Heldmann, Berenike Rogge, Martina Obst, Julia Steinhardt, Georg Brabant, Carla Moran, Krishna Chatterjee, Thomas F Münte
Apr 30, 2020
Resistance to thyroid hormone beta (RTHβ) is a syndrome of reduced responsiveness of peripheral tissue to thyroid hormone, caused by mutations in the thyroid hormone receptor beta (THRB). Its cognitive phenotype has been...
ADHD-like symptoms Action monitoring Event-related potentials Resistance to thyroid hormones TH beta receptor Thyroid hormones (TH) Adolescent Adult Aged Attention Deficit Disorder with Hyperactivity Electroencephalography Evoked Potentials Female Humans Male Middle Aged Mutation Phenotype Thyroid Hormone Receptors beta Thyroid Hormone Resistance Syndrome Young Adult
Dyslipidemia, Insulin Resistance, Ectopic Lipid Accumulation, and Vascular Function in Resistance to Thyroid Hormone β.
Carla Moran, Carmel M McEniery, Nadia Schoenmakers, Catherine Mitchell, Alison Sleigh, Laura Watson, Greta Lyons, Keith Burling, Peter Barker, Krishna Chatterjee
Jan 07, 2021
Insight Into Molecular Determinants of T3 vs T4 Recognition From Mutations in Thyroid Hormone Receptor α and β.
Karn Wejaphikul, Stefan Groeneweg, Yvonne Hilhorst-Hofstee, V Krishna Chatterjee, Robin P Peeters, Marcel E Meima, W Edward Visser
Apr 05, 2019
CONTEXT: The two major forms of circulating thyroid hormones (THs) are T3 and T4. T3 is regarded as the biologically active hormone because it binds to TH receptors (TRs) with greater affinity than T4. However, it is currently...
The Differential Diagnosis of Discrepant Thyroid Function Tests
Irene Campi, Danila Covelli, Carla Moran, Laura Fugazzola, Chiara Cacciatore, Fabio Orlandi, Gabriella Gallone, Krishna Chatterjee, Paolo Beck-Peccoz, Luca Persani
Jul 21, 2020
Background: Discrepant thyroid function tests (TFTs) are typical of inappropriate secretion of TSH (IST), a rare entity encompassing TSH-secreting adenomas (TSHoma) and Resistance to Thyroid Hormone (RTHβ) due to THRB mutations....
hyperthyroidism immuno-assay pituitary adenoma resistance to thyroid hormone thyroid hormone thyrotropin (TSH) Adolescent Adult Aged Case-Control Studies Delayed Diagnosis Diagnosis Differential Female Follow-Up Studies Humans hyperthyroidism Male Middle Aged Mutation Prognosis Retrospective Studies Thyroid Function Tests Thyroid Hormone Receptors beta Thyroid Hormones Thyroid Neoplasms Young Adult
Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight.
Saira Hameed, Michael Patterson, Waljit S Dhillo, Sofia A Rahman, Yue Ma, Christopher Holton, Apostolos Gogakos, Giles SH Yeo, Brian YH Lam, Joseph Polex-Wolf, Wiebke Fenske, Jimmy Bell, Jelena Anastasovska, Jacques Samarut, Stephen R Bloom, JH Duncan Bassett, Graham R Williams, James V Gardiner
Aug 18, 2017
The obesity epidemic is a significant global health issue. Improved understanding of the mechanisms that regulate appetite and body weight will provide the rationale for the design of anti-obesity therapies. Thyroid hormones...