Immunogenicity Testing of Lipidoids In Vitro and In Silico
Anne Marit de Groot,
Kaushik Thanki,
Monique Gangloff,
Emily Falkenberg,
Xianghui Zeng,
Djai CJ van Bijnen,
Willem van Eden,
Henrik Franzyk,
Hanne M Nielsen,
Femke Broere,
Nick J Gay,
Camilla Foged,
Alice JAM Sijts
Jun 04, 2018
Therapeutics based on small interfering RNA (siRNA) have promising potential as antiviral and anti-inflammatory agents. To deliver siRNA across cell membranes to reach the RNAi pathway in the cytosol of target cells, non-viral...