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A protein quality control pathway at the mitochondrial outer membrane.
Meredith B Metzger, Jessica L Scales, Mitchell F Dunklebarger, Jadranka Loncarek, Allan M Weissman
Apr 06, 2020
Maintaining the essential functions of mitochondria requires mechanisms to recognize and remove misfolded proteins. However, quality control (QC) pathways for misfolded mitochondrial proteins remain poorly defined. Here, we...
MAD S. cerevisiae UPS Cell Biology misfolded Quality Control Yeast Cytosol Intracellular Membranes Mitochondrial Proteins Molecular Chaperones Proteasome Endopeptidase Complex Protein Binding Protein Transport Proteolysis Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Temperature Ubiquitin Ubiquitin-Protein Ligases