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Elevated Diastolic Closing Margin Is Associated with Intraventricular Hemorrhage in Premature Infants.
Christopher J Rhee, Jeffrey R Kaiser, Danielle R Rios, Kathleen K Kibler, R Blaine Easley, Dean B Andropoulos, Marek Czosnyka, Peter Smielewski, Georgios V Varsos, Craig G Rusin, C Heath Gauss, D Keith Williams, Ken M Brady
Jun 17, 2016
The relationship between human placental morphometry and ultrasonic measurements of utero-placental blood flow and fetal growth.
Burden of hypoxia and intraventricular haemorrhage in extremely preterm infants.
Isabel Hui Xuan Ng, Cristine Sortica da Costa, Fred A Zeiler, Flora Y Wong, Peter Smielewski, Marek Czosnyka, Topun Austin
Feb 24, 2020
OBJECTIVE: Thresholds of cerebral hypoxia through monitoring of near-infrared spectroscopy tissue oxygenation index (TOI) were used to investigate the relationship between intraventricular haemorrhage (IVH) and indices of...
Imaging Monitoring Neonatology Neurodevelopment neurodisability Catheterization cerebral hemorrhage Cerebrovascular Circulation Female Gestational Age Humans Hypoxia Brain Infant Newborn Infant Premature Diseases Intensive Care Units Neonatal Male Prospective Studies spectroscopy Near-Infrared Umbilical Arteries
Pathophysiology of placental-derived fetal growth restriction.
Placental-related fetal growth restriction arises primarily due to deficient remodeling of the uterine spiral arteries supplying the placenta during early pregnancy. The resultant malperfusion induces cell stress within the...
AKT/mTOR Apoptosis atherosis chorion laeve electron transport chain extravillous trophoblast failure of physiologic transformation fetal growth restriction fetoplacental weight ratio Hemochorial placentation interstitial trophoblast intervillous space intraplacental oxygen concentration Mitochondria Oxidative Stress perivillous fibrin deposition Placenta placental infarct placental inflammation placental location Reactive Oxygen Species spiral arteries ultrasound imaging Unfolded Protein Response villi regression villous hypoplasia Chorionic Villi Female Fetal Growth Retardation Gene Expression Regulation Genomic Imprinting Humans Magnetic Resonance Imaging Maternal-Fetal Exchange Placenta Placental Circulation Placental Insufficiency Placentation pre-eclampsia Pregnancy Stress Physiological Trophoblasts Ultrasonography Prenatal Umbilical Arteries Uterine Artery Vascular Remodeling
Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction.
Tu'uhevaha J Kaitu'u-Lino, Teresa M MacDonald, Ping Cannon, Tuong-Vi Nguyen, Richard J Hiscock, Nick Haan, Jenny E Myers, Roxanne Hastie, Kirsten M Dane, Anna L Middleton, Intissar Bittar, Amanda N Sferruzzi-Perri, Natasha Pritchard, Alesia Harper, Natalie J Hannan, Valerie Kyritsis, Nick Crinis, Lisa Hui, Susan P Walker, Stephen Tong
Jul 17, 2020
Placental insufficiency can cause fetal growth restriction and stillbirth. There are no reliable screening tests for placental insufficiency, especially near-term gestation when the risk of stillbirth rises. Here we show a...
Animals Anthropometry Biomarkers Female Fetal Growth Retardation Humans Infant Newborn Infant Small for Gestational Age Mice Placenta Placental Insufficiency Plethysmography Predictive Value of Tests Pregnancy Pregnancy Trimester Third Proteinase Inhibitory Proteins Secretory Sensitivity and Specificity Ultrasonography Prenatal Umbilical Arteries Uterine Artery
Fetal umbilical artery Doppler as a tool for universal third trimester screening
Alexandros A Moraitis, Thomas Bainton, Ulla Sovio, Peter Brocklehurst, Alexander EP Heazell, Jim G Thornton, Stephen C Robson, Aris Papageorghiou, Gordon CS Smith
Mar 24, 2021
The objective of this study was to investigate the accuracy of universal third trimester umbilical artery (UA) Doppler to predict adverse pregnancy outcome at term. We searched Medline, EMBASE, the Cochrane library and...
Birth weight to placenta weight ratio and its relationship to ultrasonic measurements, maternal and neonatal morbidity
N Salavati, SJ Gordijn, U Sovio, R Zill-E-Huma, A Gebril, DS Charnock-Jones, SA Scherjon, Gcs Smith
Mar 09, 2018
INTRODUCTION: Birth weight to placenta weight (BWPW)-ratio is an indicator of the ability of the placenta to maintain adequate nutrient supply to the fetus. We sought to investigate the relationship between BWPW-ratio with fetal...
Independent influences of maternal obesity and fetal sex on maternal cardiovascular adaptation to pregnancy
Noor EWD Teulings, Angela M Wood, Ulla Sovio, Susan E Ozanne, Gordon CS Smith, Catherine E Aiken
Apr 03, 2020
Trans-abdominal in vivo placental vessel occlusion using High Intensity Focused Ultrasound.
Caroline J Shaw, Ian Rivens, John Civale, Kimberley J Botting, Gail Ter Haar, Dino A Giussani, Christoph C Lees
Nov 22, 2018
Pre-clinically, High Intensity Focused Ultrasound (HIFU) has been shown to safely and effectively occlude placental blood vessels in the acute setting, when applied through the uterus. However, further development of the...