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Genomic Surveillance of Enterococcus faecium Reveals Limited Sharing of Strains and Resistance Genes between Livestock and Humans in the United Kingdom.
Theodore Gouliouris, Kathy E Raven, Catherine Ludden, Beth Blane, Jukka Corander, Carolyne S Horner, Juan Hernandez-Garcia, Paul Wood, Nazreen F Hadjirin, Milorad Radakovic, Mark A Holmes, Marcus de Goffau, Nicholas M Brown, Julian Parkhill, Sharon J Peacock
Dec 03, 2018
Vancomycin-resistant Enterococcus faecium (VREfm) is a major cause of nosocomial infection and is categorized as high priority by the World Health Organization global priority list of antibiotic-resistant bacteria. In the past...
Enterococcus faecium One Health genome sequencing Livestock vancomycin resistant vancomycin-resistant Animals Anti-Bacterial Agents Cross-Sectional Studies Drug Resistance Multiple Bacterial Enterococcus faecium Epidemiological Monitoring Farms Genome Bacterial Genotype Gram-Positive Bacterial Infections Humans Livestock Meat Products Microbial Sensitivity Tests Phylogeny Polymorphism Single Nucleotide prevalence Swine United Kingdom Vancomycin Resistance Vancomycin-Resistant Enterococci Wastewater whole genome sequencing
Comparison of two chromogenic media for the detection of vancomycin-resistant enterococcal carriage by nursing home residents.
Theodore Gouliouris, Beth Blane, Hayley J Brodrick, Kathy E Raven, Kirsty E Ambridge, Angela D Kidney, Nazreen F Hadjirin, M Estée Török, Direk Limmathurotsakul, Sharon J Peacock
May 13, 2016
detection Enterococcus faecium Selectivity sensitivity VRE Vancomycin-Resistant Enterococci Bacteriological Techniques Carrier State Chromogenic Compounds Culture Media Enterococcus faecalis Enterococcus faecium Feces Gram-Positive Bacterial Infections Humans Nursing Homes Prospective Studies Sensitivity and Specificity Vancomycin-Resistant Enterococci
Quantifying acquisition and transmission of Enterococcus faecium using genomic surveillance.
Theodore Gouliouris, Francesc Coll, Catherine Ludden, Beth Blane, Kathy E Raven, Plamena Naydenova, Charles Crawley, Mili Estée Török, David A Enoch, Nicholas M Brown, Ewan M Harrison, Julian Parkhill, Sharon J Peacock
Aug 14, 2020
Nosocomial acquisition and transmission of vancomycin-resistant Enterococcus faecium (VREfm) is the driver for E. faecium carriage in hospitalized patients, which, in turn, is a risk factor for invasive infection in...
Adult Aged Aged 80 and over Alcohols Anti-Bacterial Agents Chlorhexidine Cross Infection Disease Outbreaks Disinfectants Enterococcus faecium Genome Bacterial Gram-Positive Bacterial Infections Humans infection control Microbial Sensitivity Tests Middle Aged Prospective Studies vancomycin Vancomycin-Resistant Enterococci whole genome sequencing Young Adult
Complex Routes of Nosocomial Vancomycin-Resistant Enterococcus faecium Transmission Revealed by Genome Sequencing.
Kathy E Raven, Theodore Gouliouris, Hayley Brodrick, Francesc Coll, Nicholas M Brown, Rosy Reynolds, Sandra Reuter, M Estée Török, Julian Parkhill, Sharon J Peacock
Mar 09, 2017
Enterococcus faecium genome sequencing. infection control transmission vancomycin resistant Cross Infection Enterococcus faecium Genome Bacterial Gram-Positive Bacterial Infections Humans Phylogeny Polymorphism Single Nucleotide Retrospective Studies Vancomycin-Resistant Enterococci whole genome sequencing
Genome-Based Analysis of Enterococcus faecium Bacteremia Associated with Recurrent and Mixed-Strain Infection.
Vancomycin-resistant Enterococcus faecium (VREfm) bloodstream infections are associated with high recurrence rates. This study used genome sequencing to accurately distinguish the frequency of relapse and reinfection in patients...
VRE Mixed infection Recurrence Adolescent Adult Aged Anti-Bacterial Agents Bacteremia Child Coinfection Cross Infection Enterococcus faecium Female Genome Bacterial Gram-Positive Bacterial Infections Hospitals University Humans Infant Newborn Male Microbial Sensitivity Tests Middle Aged Polymorphism Single Nucleotide Recurrence Retrospective Studies United Kingdom Vancomycin-Resistant Enterococci Young Adult
Genome-based characterization of hospital-adapted Enterococcus faecalis lineages.
Kathy E Raven, Sandra Reuter, Theodore Gouliouris, Rosy Reynolds, Julie E Russell, Nicholas M Brown, M Estée Török, Julian Parkhill, Sharon J Peacock
Dec 10, 2015
Infectious Diseases Biodefense Vaccine Related Antimicrobial resistance Prevention Genetics Infection Bacteremia Cross Infection Enterococcus faecalis Genome Bacterial Genotype Gram-Positive Bacterial Infections Hospitals Ireland molecular epidemiology Phylogeography Sequence Analysis DNA United Kingdom Vancomycin-Resistant Enterococci Virulence Factors
Whole-genome sequencing reveals transmission of vancomycin-resistant Enterococcus faecium in a healthcare network.
Hayley J Brodrick, Kathy E Raven, Ewan M Harrison, Beth Blane, Sandra Reuter, M Estée Török, Julian Parkhill, Sharon J Peacock
Dec 18, 2015
Colonisation with ESBL-producing and carbapenemase-producing Enterobacteriaceae, vancomycin-resistant enterococci, and meticillin-resistant Staphylococcus aureus in a long-term care facility over one year.
Catherine Ludden, Martin Cormican, Akke Vellinga, James R Johnson, Bernie Austin, Dearbháile Morris
Sep 29, 2016
BACKGROUND: This study examined colonisation with and characteristics of antimicrobial-resistant organisms among residents of a long-term care facility (LTCF) over one year, including strain persistence and molecular diversity...
Aged Aged 80 and over Bacterial Proteins Carrier State Electrophoresis Gel Pulsed-Field Enterobacteriaceae Enterobacteriaceae Infections Escherichia coli Escherichia coli Infections Female Gram-Negative Bacterial Infections Gram-Positive Bacterial Infections Humans Klebsiella Infections Klebsiella pneumoniae Long-Term Care Male Methicillin Methicillin-Resistant Staphylococcus aureus molecular epidemiology Nursing Homes Polymerase Chain Reaction Staphylococcal Infections Vancomycin-Resistant Enterococci beta-Lactamases
Genome-based characterization of hospital-adapted Enterococcus faecalis lineages.
Kathy E Raven, Sandra Reuter, Theodore Gouliouris, Rosy Reynolds, Julie E Russell, Nicholas M Brown, M Estée Török, Julian Parkhill, Sharon J Peacock
Mar 19, 2019
Vancomycin-resistant Enterococcus faecalis (VREfs) is an important nosocomial pathogen(1,2). We undertook whole genome sequencing of E. faecalis associated with bloodstream infection in the UK and Ireland over more than a decade...
Bacteremia Cross Infection Enterococcus faecalis Genome Bacterial Genotype Gram-Positive Bacterial Infections Hospitals Ireland molecular epidemiology Phylogeography Sequence Analysis DNA United Kingdom Vancomycin-Resistant Enterococci Virulence Factors
Published by: Nat Microbiol
Point-prevalence survey of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant enterococci in adult inpatients in a university teaching hospital in the UK.
Infections with carbapenemase-producing Enterobacteriaceae (CPE) and vancomycin-resistant enterococci (VRE) are associated with increased morbidity and mortality, but the carriage rates of CRE and VRE among hospital inpatients...
CPE carriage prevalence SURVEILLANCE VRE Adolescent Adult Aged Aged 80 and over Carbapenem-Resistant Enterobacteriaceae Carrier State Enterobacteriaceae Infections Female Gram-Positive Bacterial Infections Hospitals University Humans Inpatients Male Middle Aged prevalence Surveys and Questionnaires United Kingdom Vancomycin-Resistant Enterococci Young Adult