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Results: 12
Patient safety, self-injection, and B12 deficiency
Natasha Tyler, Alexander Hodkinson, Naeem Ahlam, Sally Giles, Andrew Zhou, Maria Panagioti
Nov 03, 2022
BACKGROUND: Individuals with vitamin B12 deficiency (including pernicious anaemia) often report being 'let down' or stigmatised by general practice systems and policy, and choose instead to self-medicate via injection; the...
Cross-exchange of B-vitamins underpins a mutualistic interaction between Ostreococcus tauri and Dinoroseobacter shibae.
Matthew B Cooper, Elena Kazamia, Katherine E Helliwell, Ulrich Johan Kudahl, Andrew Sayer, Glen L Wheeler, Alison G Smith
Sep 21, 2018
Exploring the onset of B12 -based mutualisms using a recently evolved Chlamydomonas auxotroph and B12 -producing bacteria.
Freddy Bunbury, Evelyne Deery, Andrew P Sayer, Vaibhav Bhardwaj, Ellen L Harrison, Martin J Warren, Alison G Smith
May 20, 2022
Cobalamin (vitamin B12 ) is a cofactor for essential metabolic reactions in multiple eukaryotic taxa, including major primary producers such as algae, and yet only prokaryotes can produce it. Many bacteria can colonize the algal...
One-carbon metabolism biomarkers and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition.
Alina Vrieling, H Bas Bueno-De-Mesquita, Martine M Ros, Ellen Kampman, Katja K Aben, Frederike L Büchner, Eugène H Jansen, Nina Roswall, Anne Tjønneland, Marie-Christine Boutron-Ruault, Claire Cadeau, Jenny Chang-Claude, Rudolf Kaaks, Steffen Weikert, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Sabina Sieri, Domenico Palli, Salvatore Panico, Petra H Peeters, Elisabete Weiderpass, Guri Skeie, Paula Jakszyn, María-Dolores Chirlaque, Eva Ardanaz, María-José Sánchez, Roy Ehrnström, Johan Malm, Börje Ljungberg, Kay-Tee Khaw, Nick J Wareham, Paul Brennan, Mattias Johansson, Elio Riboli, Lambertus A Kiemeney
Feb 11, 2019
B-vitamins biomarker folate nested case-control urothelial cell carcinomas Aged Biomarkers Tumor Carcinoma Transitional Cell Case-Control Studies Female Folic Acid homocysteine Humans Male Middle Aged Odds Ratio Prospective Studies Risk Assessment Smoking Urinary Bladder Neoplasms Vitamin B 12 Vitamin B 6
Genetically predicted circulating B vitamins in relation to digestive system cancers.
Shuai Yuan, Paul Carter, Mathew Vithayathil, Siddhartha Kar, Amy M Mason, Stephen Burgess, Susanna C Larsson
Mar 30, 2021
BACKGROUND: Folate, vitamin B6 and vitamin B12 have been associated with digestive system cancers. We conducted a two-sample Mendelian randomisation study to assess the causality of these associations. METHODS: Two, one and 14...
Adult Anemia Pernicious Case-Control Studies Digestive System Neoplasms Female Folic Acid Genetic Association Studies Genetic Predisposition to Disease Genetic Testing Humans Male Mendelian Randomization Analysis Polymorphism Single Nucleotide Risk Factors Sweden United Kingdom Vitamin B 12 Vitamin B 6 Vitamin B Complex Vitamin B Deficiency
Delayed Processing of Chilled Whole Blood for 24 Hours Does Not Affect the Concentration of the Majority of Micronutrient Status Biomarkers.
Kerry S Jones, Sarah R Meadows, Karen Chamberlain, Damon A Parkington, Dave Collins, Polly Page, Albert Koulman
Jul 23, 2021
Combining SIMS and mechanistic modelling to reveal nutrient kinetics in an algal-bacterial mutualism.
Hannah Laeverenz Schlogelhofer, François J Peaudecerf, Freddy Bunbury, Martin J Whitehouse, Rachel A Foster, Alison G Smith, Ottavio A Croze
Jul 20, 2021
Microbial communities are of considerable significance for biogeochemical processes, for the health of both animals and plants, and for biotechnological purposes. A key feature of microbial interactions is the exchange of...
Drug delivery from a solid formulation during breastfeeding-A feasibility study with mothers and infants.
Theresa Maier, Paula Peirce, Laura Baird, Sophie L Whitehouse, Nigel Kh Slater, Kathryn Beardsall
Mar 04, 2022
Fundamental shift in vitamin B12 eco-physiology of a model alga demonstrated by experimental evolution.
Katherine E Helliwell, Sinéad Collins, Elena Kazamia, Saul Purton, Glen L Wheeler, Alison G Smith
Nov 20, 2014
Homocysteine, B vitamins, and cardiovascular disease
BACKGROUND: Whether a modestly elevated homocysteine level is causally associated with an increased risk of cardiovascular disease remains unestablished. We conducted a Mendelian randomization study to assess the associations of...
Cyanobacteria and Eukaryotic Algae Use Different Chemical Variants of Vitamin B12.
Katherine Emma Helliwell, Andrew David Lawrence, Andre Holzer, Ulrich Johan Kudahl, Severin Sasso, Bernhard Kräutler, David John Scanlan, Martin James Warren, Alison Gail Smith
Feb 19, 2016
Homocysteine and small vessel stroke
OBJECTIVE: Trials of B vitamin therapy to lower blood total homocysteine (tHcy) levels for prevention of stroke are inconclusive. Secondary analyses of trial data and epidemiological studies suggest that tHcy levels may be...