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Systematic Nanoscale Analysis of Endocytosis Links Efficient Vesicle Formation to Patterned Actin Nucleation.
Markus Mund, Johannes Albertus van der Beek, Joran Deschamps, Serge Dmitrieff, Philipp Hoess, Jooske Louise Monster, Andrea Picco, François Nédélec, Marko Kaksonen, Jonas Ries
Nov 16, 2020
Clathrin-mediated endocytosis is an essential cellular function in all eukaryotes that is driven by a self-assembled macromolecular machine of over 50 different proteins in tens to hundreds of copies. How these proteins are...
Brownian dynamics simulations SMLM WASP actin Clathrin Endocytosis high-throughput single-molecule localization microscopy superresolution microscopy Actin Cytoskeleton Actins Cell Membrane Endocytosis Microscopy Fluorescence Models Theoretical Protein Conformation Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Secretory Vesicles Wiskott-Aldrich Syndrome Protein Family