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Results: 22
Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells.
Justyna Ulanska-Poutanen, Jakub Mieczkowski, Chao Zhao, Katarzyna Konarzewska, Beata Kaza, Hartmut Bf Pohl, Lukasz Bugajski, Bozena Kaminska, Robin Jm Franklin, Malgorzata Zawadzka
Nov 19, 2018
Schwann Cells adult CNS progenitors neuroscience perivascular niche rat remyelination Animals Astrocytes Bone Morphogenetic Proteins Cell Differentiation Cellular Microenvironment Central Nervous System Demyelinating Diseases Endothelial Cells Gene Expression Regulation Ligands Oligodendroglia Peripheral Nervous System RNA Messenger Rats Stem Cell Niche Stem Cells Wnt Signaling Pathway Wounds and Injuries
Weapon injuries in the crusader mass graves from a 13th century attack on the port city of Sidon (Lebanon).
Richard NR Mikulski, Holger Schutkowski, Martin J Smith, Claude Doumet-Serhal, Piers D Mitchell
Sep 25, 2021
Archaeological excavations close to St Louis' castle in Sidon, Lebanon have revealed two mass grave deposits containing partially articulated and disarticulated human skeletal remains. A minimum of 25 male individuals have been...
Carrel, A. The treatment of infected wounds
The Rockefeller University
Jan 01, 0001
Alexis Carrel. The treatment of infected wounds
Shortly after the outbreak of the war, Alexis Carrel, in collaboration with H. D. Dakin ( Herter Laboratories, New York), seeking to discover the best means of treating war-wound...
Published by: Hoeber
Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish.
Caroline Coombs, Antonios Georgantzoglou, Hazel A Walker, Julian Patt, Nicole Merten, Hugo Poplimont, Elisabeth M Busch-Nentwich, Sarah Williams, Christina Kotsi, Evi Kostenis, Milka Sarris
Oct 17, 2019
Immune cells congregate at specific loci to fight infections during inflammatory responses, a process that must be transient and self-resolving. Cell dispersal promotes resolution, but it remains unclear how transition from...
A consensus statement for trauma surgery capacity building in Latin America.
Mohini Dasari, Erica D Johnson, Jorge H Montenegro, Dylan P Griswold, Maria Fernanda Jiménez, Juan Carlos Puyana, Andres M Rubiano, Cartagena Consensus
Jan 30, 2021
Skin models for cutaneous melioidosis reveal Burkholderia infection dynamics at wound's edge with inflammasome activation, keratinocyte extrusion and epidermal detachment.
Joanne Wei Kay Ku, Supatra Tharinee Marsh, Mui Hoon Nai, Kim Samirah Robinson, Daniel Eng Thiam Teo, Franklin Lei Zhong, Katherine A Brown, Thiam Chye Lim, Chwee Teck Lim, Yunn-Hwen Gan
Jan 07, 2022
Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm Signals.
Hugo Poplimont, Antonios Georgantzoglou, Morgane Boulch, Hazel A Walker, Caroline Coombs, Foteini Papaleonidopoulou, Milka Sarris
May 20, 2020
Neutrophils are major inflammatory cells that rapidly infiltrate wounds to provide antimicrobial functions. Within the damaged tissue, neutrophil migration behavior often switches from exploratory patrolling to coordinated...
Chemotaxis connexins Infection Inflammation leukocyte migration leukotriene Neutrophils Swarming tissue damage Wound Adenosine Triphosphate Animals Calcium Cell Aggregation Connexin 43 connexins Leukotriene B4 Neutrophil Infiltration Neutrophils Pseudomonas aeruginosa Signal Transduction Wounds and Injuries Zebrafish
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and...
Adolescent Adult Age Distribution Aged Aged 80 and over Child Child Preschool Disabled Persons Female Global Burden of Disease Global Health Humans Incidence Infant Infant Newborn Life Expectancy Male Middle Aged Morbidity prevalence Sex Distribution Socioeconomic Factors Wounds and Injuries Young Adult
Preventing intrusive memories after trauma via a brief intervention involving Tetris computer game play in the emergency department
L Iyadurai, SE Blackwell, R Meiser-Stedman, PC Watson, MB Bonsall, JR Geddes, AC Nobre, EA Holmes
Mar 29, 2018
After psychological trauma, recurrent intrusive visual memories may be distressing and disruptive. Preventive interventions post trauma are lacking. Here we test a behavioural intervention after real-life trauma derived from...
Integrins promote axonal regeneration after injury of the nervous system.
Integrins are cell surface receptors that form the link between extracellular matrix molecules of the cell environment and internal cell signalling and the cytoskeleton. They are involved in several processes, e.g. adhesion and...
Neuroregeneration and plasticity
Neuronal networks, especially those in the central nervous system (CNS), evolved to support extensive functional capabilities while ensuring stability. Several physiological "brakes" that maintain the stability of the neuronal...
Traumatic spinal cord injury
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and vocational well-being of patients. The demographic of SCIs is shifting such that an increasing proportion of older individuals are...
Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017
GBD 2017 DALYs and HALE Collaborators
Feb 08, 2019
BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and...
Control of hyperglycaemia in paediatric intensive care (CHiP)
Duncan Macrae, John Pappachan, Richard Grieve, Roger Parslow, Simon Nadel, Margrid Schindler, Paul Baines, Peter-Marc Fortune, Zdenek Slavik, Allan Goldman, Ann Truesdale, Helen Betts, Elizabeth Allen, Claire Snowdon, Deborah Percy, Michael Broadhead, Tara Quick, Mark Peters, Kevin Morris, Robert Tasker, Diana Elbourne
Jun 16, 2011
BACKGROUND: There is increasing evidence that tight blood glucose (BG) control improves outcomes in critically ill adults. Children show similar hyperglycaemic responses to surgery or critical illness. However it is not known...
Adolescent Age Factors Child Child Preschool Clinical Protocols Critical Illness Drug Monitoring England Humans Hyperglycemia Infant Infant Newborn Infusions Intravenous Insulin Intensive Care Units Pediatric Patient Selection Postoperative Complications Research Design Respiration Artificial Treatment Outcome Vasoconstrictor Agents Ventilator Weaning Wounds and Injuries
Rationale and design of the violence, injury and trauma observatory (VITO)
The establishment of violence and injury observatories elsewhere has been found to reduce the burden within a relatively short period. Currently no integrated system exists in South Africa to provide collated data on violence...
Humans Wounds and Injuries Prospective Studies Pilot Projects Research Design violence Databases Factual South Africa
Published by: BMJ Open
An exploratory qualitative study of the prevention of road traffic collisions and neurotrauma in India
Santhani M Selveindran, Gurusinghe DN Samarutilake, K Madhu Narayana Rao, Jogi V Pattisapu, Christine Hill, Angelos G Kolias, Rajesh Pathi, Peter JA Hutchinson, MV Vijaya Sekhar
Jun 11, 2021
BACKGROUND: Despite current preventative strategies, road traffic collisions (RTCs) and resultant neurotrauma remain a major problem in India. This study seeks to explore local perspectives in the context within which RTCs take...
Inter-group violence among early Holocene hunter-gatherers of West Turkana, Kenya.
M Mirazón Lahr, F Rivera, RK Power, A Mounier, B Copsey, F Crivellaro, JE Edung, JM Maillo Fernandez, C Kiarie, J Lawrence, A Leakey, E Mbua, H Miller, A Muigai, DM Mukhongo, A Van Baelen, R Wood, J-L Schwenninger, R Grün, H Achyuthan, A Wilshaw, RA Foley
Feb 12, 2016
Trauma-focused cognitive behaviour therapy versus treatment as usual for post traumatic stress disorder (PTSD) in young children aged 3 to 8 years
Tim Dalgleish, Benjamin Goodall, Isobel Chadwick, Aliza Werner-Seidler, Anna McKinnon, Nicola Morant, Susanne Schweizer, Inderpal Panesar, Ayla Humphrey, Peter Watson, Louise Lafortune, Patrick Smith, Richard Meiser-Stedman
Mar 04, 2020
BACKGROUND: Following horrific or life-threatening events approximately 10 to 15% of young children develop post traumatic stress disorder (PTSD). The symptoms of this disorder are distressing - nightmares, flashbacks, anger...
Adaptation Psychological Age Factors Child Child Behavior Child Preschool Clinical Protocols Cognitive Behavioral Therapy Comorbidity Cross-Over Studies Emotions Humans Memory Pilot Projects Research Design Stress Disorders Post-Traumatic Time Factors Treatment Outcome United Kingdom Wounds and Injuries