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Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification.
Adam C Wilkinson, Viviane KS Kawata, Judith Schütte, Xuefei Gao, Stella Antoniou, Claudia Baumann, Steven Woodhouse, Rebecca Hannah, Yosuke Tanaka, Gemma Swiers, Victoria Moignard, Jasmin Fisher, Shimauchi Hidetoshi, Marloes R Tijssen, Marella FTR de Bruijn, Pentao Liu, Berthold Göttgens
Sep 12, 2014
Haematopoiesis PU.1 Regulatory networks Transcription activator-like effectors Animals Cell Differentiation Coculture Techniques Endothelial Cells Gene Expression Profiling Gene Expression Regulation Developmental Hematopoiesis Hematopoietic Stem Cells Humans K562 Cells Mice Mice Transgenic Phenotype Proto-Oncogene Proteins Single-Cell Analysis Trans-Activators Transcription Factors Transgenes Xanthomonas