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acid-sensing ion channel dorsal root ganglia Ion channel joint nociception Pain Skin Afferent Pathways Animals Electrophysiological Phenomena Female Hydrogen-Ion Concentration Joints Mice Inbred C57BL Phenotype Sensory Receptor Cells Skin

Acid-sensing ion channels (ASICs) are members of the diverse family of degenerin/epithelial sodium channels (DEG/ENaCs). They perform a wide range of physiological roles in healthy organisms, including in gut function and...

acid-sensing ion channel Amiloride degenerin/epithelial sodium channel proton-gated Zinc

Acid-sensing ion channels (ASICs) are a family of ion channels comprised of six subunits encoded by four genes and they are expressed throughout the peripheral and central nervous systems. ASICs have been implicated in a wide...

acid-sensing ion channel Central Nervous System Comparative Study Gene Expression Housekeeping gene selection Naked mole-rat normalization Quantitative real-time PCR geNorm

acid-sensing ion channel Ion channel Skin joint dorsal root ganglia nociception Pain

TRP channel acid acid-sensing ion channel nociception proton-sensing GPCR two-pore potassium channel Acid Sensing Ion Channels Animals Biological Evolution Humans nociception Nociceptors Pain

acid acid-sensing ion channel GMQ Protons Sephin1 Acid Sensing Ion Channels Allosteric Regulation Animals CHO Cells Computer Simulation Cricetinae Cricetulus Dose-Response Relationship Drug Drug Evaluation Preclinical guanabenz Guanidines Protein Structure Secondary Quinazolines