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Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease.
Shu Mei Teo, Howard HF Tang, Danny Mok, Louise M Judd, Stephen C Watts, Kym Pham, Barbara J Holt, Merci Kusel, Michael Serralha, Niamh Troy, Yury A Bochkov, Kristine Grindle, Robert F Lemanske, Sebastian L Johnston, James E Gern, Peter D Sly, Patrick G Holt, Kathryn E Holt, Michael Inouye
Nov 12, 2018
Repeated cycles of infection-associated lower airway inflammation drive the pathogenesis of persistent wheezing disease in children. In this study, the occurrence of acute respiratory tract illnesses (ARIs) and the...
airway microbiota allergic sensitization Asthma lower respiratory infection Acute Disease Asthma Child Preschool Cohort Studies Disease Susceptibility Female Humans Hypersensitivity Immunoglobulin E Infant Longitudinal Studies Male Microbiota nasopharynx Prospective Studies Respiratory Sounds Respiratory Tract Infections Risk Factors