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Comparative Analysis of SARS-CoV-2 Variants of Concern, Including Omicron, Highlights Their Common and Distinctive Amino Acid Substitution Patterns, Especially at the Spike ORF.
Marios Nikolaidis
,
Athanasios Papakyriakou
,
Katerina Chlichlia
,
Panayotis Markoulatos
,
Stephen G Oliver
,
Grigorios D Amoutzias
May 24, 2022
In order to gain a deeper understanding of the recently emerged and highly divergent Omicron variant of concern (VoC), a study of amino acid substitution (AAS) patterns was performed and compared with those of the other four...
covid-19
Omicron
SARS-CoV-2
amino acid substitutions
dN/dS
evolution
recurrent mutations
spike
variants of concern
Amino Acid Substitution
covid-19
Humans
Phylogeny
SARS-CoV-2
Spike Glycoprotein
Coronavirus
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