Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer's disease.
Dimitrios I Sideris,
John S H Danial,
Derya Emin,
Francesco S Ruggeri,
Zengjie Xia,
Yu P Zhang,
Evgeniia Lobanova,
Helen Dakin,
Suman De,
Alyssa Miller,
Jason C Sang,
Tuomas P J Knowles,
Michele Vendruscolo,
Graham Fraser,
Damian Crowther,
David Klenerman
Sep 16, 2021
Protein aggregation likely plays a key role in the initiation and spreading of Alzheimer's disease pathology through the brain. Soluble aggregates of amyloid beta are believed to play a key role in this process. However, the...