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Dendritic Cells Charged with Apoptotic Tumor Cells Induce Long-Lived Protective CD4+ and CD8+ T Cell Immunity against B16 Melanoma
Romina S. Goldszmid
,
Juliana Idoyaga
,
Alicia Inès Bravo
Jan 01, 0001
Dendritic cells (DCs) are potent APCs and attractive vectors for cancer immunotherapy. Using the B16 melanoma, a poorly immunogenic experimental tumor that expresses low levels of MHC class I products, we investigated whether...
Apoptosis
bone marrow cell
antigen recognition
cytokine release
lymph node
lymphatic drainage
melanoma cell
tumor immunity
Published by:
Rockefeller University